Bispecific antibody characterization by a combination of intact and site-specific/chain-specific LC/MS techniques.

Duivelshof, Bastiaan L; Beck, Alain; Guillarme, Davy; D'Atri, Valentina

Duivelshof, Bastiaan L; Beck, Alain; Guillarme, Davy; D'Atri, Valentina.

Afiliação

Duivelshof BL; Institute of Pharmaceutical Sciences of Western Switzerland (ISPSO), University of Geneva, CMU-Rue Michel Servet 1, 1211, Geneva 4, Switzerland; School of Pharmaceutical Sciences, University of Geneva, CMU-Rue Michel Servet 1, 1211, Geneva 4, Switzerland.
Beck A; IRPF - Centre d'Immunologie Pierre-Fabre (CIPF), 5 Avenue Napoléon III, BP 60497, Saint-Julien-en-Genevois, France.
Guillarme D; Institute of Pharmaceutical Sciences of Western Switzerland (ISPSO), University of Geneva, CMU-Rue Michel Servet 1, 1211, Geneva 4, Switzerland; School of Pharmaceutical Sciences, University of Geneva, CMU-Rue Michel Servet 1, 1211, Geneva 4, Switzerland.
D'Atri V; Institute of Pharmaceutical Sciences of Western Switzerland (ISPSO), University of Geneva, CMU-Rue Michel Servet 1, 1211, Geneva 4, Switzerland; School of Pharmaceutical Sciences, University of Geneva, CMU-Rue Michel Servet 1, 1211, Geneva 4, Switzerland. Electronic address: valentina.datri@unige.ch

Talanta ; 236: 122836, 2022 Jan 01.

Article em En | MEDLINE | ID: mdl-34635226

Assuntos

Anticorpos Biespecíficos; Anticorpos Monoclonais; Cromatografia em Gel; Cromatografia de Fase Reversa; Espectrometria de Massas

Palavras-chave

Bispecific antibody; Emicizumab; HILIC-MS; Hemlibra; IEX-MS; RPLC-MS; SEC-MS

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anticorpos Biespecíficos Idioma: En Revista: Talanta Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Suíça País de publicação: Holanda

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