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Activation of Notch and Myc Signaling via B-cell-Restricted Depletion of Dnmt3a Generates a Consistent Murine Model of Chronic Lymphocytic Leukemia.
Biran, Anat; Yin, Shanye; Kretzmer, Helene; Ten Hacken, Elisa; Parvin, Salma; Lucas, Fabienne; Uduman, Mohamed; Gutierrez, Catherine; Dangle, Nathan; Billington, Leah; Regis, Fara Faye; Rassenti, Laura Z; Mohammad, Arman; Hoffmann, Gabriela Brunsting; Stevenson, Kristen; Zheng, Mei; Witten, Elizabeth; Fernandes, Stacey M; Tausch, Eugen; Sun, Clare; Stilgenbauer, Stephan; Brown, Jennifer R; Kipps, Thomas J; Aster, John C; Gnirke, Andreas; Neuberg, Donna S; Letai, Anthony; Wang, Lili; Carrasco, Ruben D; Meissner, Alexander; Wu, Catherine J.
Afiliação
  • Biran A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Yin S; Harvard Medical School, Boston, Massachusetts.
  • Kretzmer H; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Ten Hacken E; Harvard Medical School, Boston, Massachusetts.
  • Parvin S; Department of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany.
  • Lucas F; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Uduman M; Harvard Medical School, Boston, Massachusetts.
  • Gutierrez C; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Dangle N; Harvard Medical School, Boston, Massachusetts.
  • Billington L; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
  • Regis FF; Center for Immuno-Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.
  • Rassenti LZ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Mohammad A; Harvard Medical School, Boston, Massachusetts.
  • Hoffmann GB; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Stevenson K; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Zheng M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Witten E; Moores Cancer Center, University of California San Diego Health, La Jolla, California.
  • Fernandes SM; Broad Institute of MIT and Harvard, Cambridge, Massachusetts.
  • Tausch E; Department of Data Science, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.
  • Sun C; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Stilgenbauer S; Department of Data Science, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.
  • Brown JR; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
  • Kipps TJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Aster JC; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Gnirke A; Department of Internal Medicine III, Ulm University, Ulm, Germany.
  • Neuberg DS; Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland.
  • Letai A; Department of Internal Medicine III, Ulm University, Ulm, Germany.
  • Wang L; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Carrasco RD; Harvard Medical School, Boston, Massachusetts.
  • Meissner A; Moores Cancer Center, University of California San Diego Health, La Jolla, California.
  • Wu CJ; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Cancer Res ; 81(24): 6117-6130, 2021 12 15.
Article em En | MEDLINE | ID: mdl-34686499
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Linfocítica Crônica de Células B / Proteínas Proto-Oncogênicas c-myc / Resistencia a Medicamentos Antineoplásicos / Modelos Animais de Doenças / Receptores Notch / DNA Metiltransferase 3A Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Cancer Res Ano de publicação: 2021 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Linfocítica Crônica de Células B / Proteínas Proto-Oncogênicas c-myc / Resistencia a Medicamentos Antineoplásicos / Modelos Animais de Doenças / Receptores Notch / DNA Metiltransferase 3A Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Cancer Res Ano de publicação: 2021 Tipo de documento: Article País de publicação: Estados Unidos