Soil-transmitted helminth infections after mass drug administration for lymphatic filariasis in rural southern India.
Trop Med Int Health
; 27(1): 81-91, 2022 01.
Article
em En
| MEDLINE
| ID: mdl-34704320
ABSTRACT
OBJECTIVES:
Targeted deworming is the current strategy for control of morbidity associated with soil-transmitted helminths (STH) among at-risk populations preschool-aged children, school-aged children and women of childbearing age. We report the prevalence and intensity of STH in a district after lymphatic filariasis (LF) mass drug administration (MDA) in southern India where albendazole was co-administered from 2001.METHODS:
Children aged 2 to 15 years and adults (defined as ≥15 years) in a rural administrative block of Tamil Nadu were recruited using a probability proportional to size method. Stool samples were screened and eggs per gram (EPG) determined by Kato-Katz method. Multilevel logistic regression (MLR) and multilevel negative binomial regression (MNBR) analyses were used to identify factors associated with infection and intensity, respectively.RESULTS:
Of 862 participants who provided samples, 60 (7.0%; 95% confidence interval (CI) 5.3-8.7) were positive for STH with a predominance of hookworm infections (n = 57, 6.6%; 95% CI 5.0-8.3). Increasing age (odds ratio (OR) 1.09; 95% CI 1.04-1.15) and regular usage of the toilet (OR 0.32; 95% CI 0.12-0.88) were independently associated with hookworm infection and age was significantly associated with increasing intensity of hookworm infection (infection intensity ratio (IIR) 1.28; 95% CI 1.19-1.37). A brief review of STH prevalence in endemic settings before and after the stoppage of LF MDA indicated that, in most settings, a substantial reduction in STH prevalence is seen.CONCLUSION:
Community-wide MDA in all age groups in these post-LF MDA districts with low prevalence and light intensity infections could result in transmission interruption of STH.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Microbiologia do Solo
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Filariose Linfática
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Albendazol
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Anti-Helmínticos
Tipo de estudo:
Observational_studies
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Prevalence_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adolescent
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Adult
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Aged
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Animals
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Child
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Child, preschool
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Female
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Humans
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Infant
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Male
País/Região como assunto:
Asia
Idioma:
En
Revista:
Trop Med Int Health
Assunto da revista:
MEDICINA TROPICAL
/
SAUDE PUBLICA
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Índia