Efficient drug delivery by novel cell-penetrating peptide derived from Midkine, with two heparin binding sites braced by a length-specific helix.

Chen, Yihui; Li, Si; Zhao, Jian; Cao, Xuewei; Wang, Fujun

Chen, Yihui; Li, Si; Zhao, Jian; Cao, Xuewei; Wang, Fujun.

Afiliação

Chen Y; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, People's Republic of China.
Li S; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, People's Republic of China.
Zhao J; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, People's Republic of China.
Cao X; Department of Applied Biology, East China University of Science and Technology, Shanghai, People's Republic of China.
Wang F; State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, People's Republic of China.

J Drug Target ; 30(3): 326-333, 2022 03.

Article em En | MEDLINE | ID: mdl-34708678

Assuntos

Peptídeos Penetradores de Células; Sítios de Ligação; Peptídeos Penetradores de Células/metabolismo; Sistemas de Liberação de Medicamentos/métodos; Células HeLa; Heparina/metabolismo; Humanos; Midkina

Palavras-chave

Cell-penetrating peptide; HSPGs; Midkine; tumour-targeted delivery; α-helix

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos Penetradores de Células Limite: Humans Idioma: En Revista: J Drug Target Assunto da revista: FARMACOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de publicação: Reino Unido

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