Transient yet Robust Expression of Proteins in the Mouse Liver via Intravenous Injection of Lipid Nanoparticle-encapsulated Nucleoside-modified mRNA.

Everton, Elissa; Rizvi, Fatima; Smith, Anna R; Beattie, Mitchell; Tam, Ying; Pardi, Norbert; Weissman, Drew; Gouon-Evans, Valerie

Everton, Elissa; Rizvi, Fatima; Smith, Anna R; Beattie, Mitchell; Tam, Ying; Pardi, Norbert; Weissman, Drew; Gouon-Evans, Valerie.

Afiliação

Everton E; Center for Regenerative Medicine and the Section of Gastroenterology, Boston University and Boston Medical Center, Boston, USA.
Rizvi F; Center for Regenerative Medicine and the Section of Gastroenterology, Boston University and Boston Medical Center, Boston, USA.
Smith AR; Center for Regenerative Medicine and the Section of Gastroenterology, Boston University and Boston Medical Center, Boston, USA.
Beattie M; Acuitas Therapeutics, Vancouver, Canada.
Tam Y; Acuitas Therapeutics, Vancouver, Canada.
Pardi N; Department of Medicine, University of Pennsylvania, Philadelphia, USA.
Weissman D; Department of Medicine, University of Pennsylvania, Philadelphia, USA.
Gouon-Evans V; Center for Regenerative Medicine and the Section of Gastroenterology, Boston University and Boston Medical Center, Boston, USA.

Bio Protoc ; 11(19): e4184, 2021 Oct 05.

Article em En | MEDLINE | ID: mdl-34722830

Palavras-chave

Lipid nanoparticle; Liver regeneration; Nucleoside-modified mRNA; Protein expression; Retro-orbital injection

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Guideline Idioma: En Revista: Bio Protoc Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos

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