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Discovery of the Triazolo[1,5-a]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance.
Wang, Shuai; Wang, Sai-Qi; Teng, Qiu-Xu; Lei, Zi-Ning; Chen, Zhe-Sheng; Chen, Xiao-Bing; Liu, Hong-Min; Yu, Bin.
Afiliação
  • Wang S; School of Pharmaceutical Sciences & Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, Zhengzhou University, Zhengzhou 450001, China.
  • Wang SQ; Department of Oncology, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Henan Cancer Institute, Zhengzhou 450008, China.
  • Teng QX; College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, United States.
  • Lei ZN; College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, United States.
  • Chen ZS; College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, United States.
  • Chen XB; Department of Oncology, The Affiliated Cancer Hospital of Zhengzhou University, Henan Cancer Hospital, Henan Cancer Institute, Zhengzhou 450008, China.
  • Liu HM; School of Pharmaceutical Sciences & Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, Zhengzhou University, Zhengzhou 450001, China.
  • Yu B; School of Pharmaceutical Sciences & Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, Zhengzhou University, Zhengzhou 450001, China.
J Med Chem ; 64(21): 16187-16204, 2021 11 11.
Article em En | MEDLINE | ID: mdl-34723530
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Triazóis / Resistência a Múltiplos Medicamentos / Descoberta de Drogas Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Triazóis / Resistência a Múltiplos Medicamentos / Descoberta de Drogas Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos