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The epidemiology is promising, but the trial evidence is weak. Why pharmacological dementia risk reduction trials haven't lived up to expectations, and where do we go from here?
Peters, Ruth; Dodge, Hiroko H; James, Sarah; Jicha, Gregory A; Meyer, Pierre-Francois; Richards, Marcus; Smith, A David; Yassine, Hussein N; Abner, Erin; Hainsworth, Atticus H; Kehoe, Patrick G; Beckett, Nigel; Anderson, Craig S; Anstey, Kaarin J.
Afiliação
  • Peters R; Neuroscience Research, Randwick, New South Wales, Australia.
  • Dodge HH; Department of Psychology, University of New South Wales, Sydney, New South Wales, Australia.
  • James S; Department of Neurology, Oregon Health & Science University, Portland, Oregon, USA.
  • Jicha GA; MRC Unit for Lifelong Health and Ageing at UCL, University College London, London, UK.
  • Meyer PF; University of Kentucky, Lexington, Kentucky, USA.
  • Richards M; Center for Studies on the Prevention of Alzheimer's Disease (PREVENT-AD), Verdun, Québec, Canada.
  • Smith AD; MRC Unit for Lifelong Health and Ageing at UCL, University College London, London, UK.
  • Yassine HN; OPTIMA, Department of Pharmacology, University of Oxford, Oxford, UK.
  • Abner E; Departments of Medicine and Neurology, University of Southern California, Los Angeles, California, USA.
  • Hainsworth AH; University of Kentucky, Lexington, Kentucky, USA.
  • Kehoe PG; Molecular and Clinical Sciences Research Institute, St Georges, University of London, London, UK.
  • Beckett N; Department of Neurology, St George's Hospital, London, UK.
  • Anderson CS; Bristol Medical School University of Bristol, Bristol, UK.
  • Anstey KJ; Guys and St Thomas' NHS Foundation Trust, London, UK.
Alzheimers Dement ; 18(3): 507-512, 2022 03.
Article em En | MEDLINE | ID: mdl-34726352
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Demência / Disfunção Cognitiva Tipo de estudo: Etiology_studies / Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limite: Humans Idioma: En Revista: Alzheimers Dement Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Austrália País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Demência / Disfunção Cognitiva Tipo de estudo: Etiology_studies / Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Limite: Humans Idioma: En Revista: Alzheimers Dement Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Austrália País de publicação: Estados Unidos