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Antibacterial activity of apramycin at acidic pH warrants wide therapeutic window in the treatment of complicated urinary tract infections and acute pyelonephritis.
Becker, Katja; Cao, Sha; Nilsson, Anna; Erlandsson, Maria; Hotop, Sven-Kevin; Kuka, Janis; Hansen, Jon; Haldimann, Klara; Grinberga, Solveiga; Berruga-Fernández, Talia; Huseby, Douglas L; Shariatgorji, Reza; Lindmark, Evelina; Platzack, Björn; Böttger, Erik C; Crich, David; Friberg, Lena E; Vingsbo Lundberg, Carina; Hughes, Diarmaid; Brönstrup, Mark; Andrén, Per E; Liepinsh, Edgars; Hobbie, Sven N.
Afiliação
  • Becker K; Institute of Medical Microbiology, University of Zurich, Gloriastrasse 30, CH-8006 Zurich, Switzerland.
  • Cao S; Department of Medical Biochemistry and Microbiology, Uppsala University, Box 582, 751 23 Uppsala, Sweden.
  • Nilsson A; Department of Pharmaceutical Biosciences, Uppsala University, Box 591, 751 24 Uppsala, Sweden; Science for Life Laboratory, Uppsala University, Box 591, 751 24 Uppsala, Sweden.
  • Erlandsson M; RISE Research Institutes of Sweden, Forskargatan 20G, 151 36 Södertälje, Sweden.
  • Hotop SK; Helmholtz Centre for Infection Research, Inhoffenstrasse 7, D-38124 Braunschweig, Germany.
  • Kuka J; Latvian Institute of Organic Synthesis, Aizkraukles 21, LV-1006 Riga, Latvia.
  • Hansen J; Statens Serum Institute, Artillerivej 5, DK-2300 Copenhagen, Denmark.
  • Haldimann K; Institute of Medical Microbiology, University of Zurich, Gloriastrasse 30, CH-8006 Zurich, Switzerland.
  • Grinberga S; Latvian Institute of Organic Synthesis, Aizkraukles 21, LV-1006 Riga, Latvia.
  • Berruga-Fernández T; Department of Medical Biochemistry and Microbiology, Uppsala University, Box 582, 751 23 Uppsala, Sweden.
  • Huseby DL; Department of Medical Biochemistry and Microbiology, Uppsala University, Box 582, 751 23 Uppsala, Sweden.
  • Shariatgorji R; Department of Pharmaceutical Biosciences, Uppsala University, Box 591, 751 24 Uppsala, Sweden; Science for Life Laboratory, Uppsala University, Box 591, 751 24 Uppsala, Sweden.
  • Lindmark E; RISE Research Institutes of Sweden, Forskargatan 20G, 151 36 Södertälje, Sweden.
  • Platzack B; RISE Research Institutes of Sweden, Forskargatan 20G, 151 36 Södertälje, Sweden.
  • Böttger EC; Institute of Medical Microbiology, University of Zurich, Gloriastrasse 30, CH-8006 Zurich, Switzerland.
  • Crich D; Department of Pharmaceutical and Biomedical Sciences, University of Georgia, 250 W. Green Street, Athens, GA 30602, USA.
  • Friberg LE; Department of Pharmacy, Uppsala University, Box 580, 751 23 Uppsala, Sweden.
  • Vingsbo Lundberg C; Statens Serum Institute, Artillerivej 5, DK-2300 Copenhagen, Denmark.
  • Hughes D; Department of Medical Biochemistry and Microbiology, Uppsala University, Box 582, 751 23 Uppsala, Sweden.
  • Brönstrup M; Helmholtz Centre for Infection Research, Inhoffenstrasse 7, D-38124 Braunschweig, Germany.
  • Andrén PE; Department of Pharmaceutical Biosciences, Uppsala University, Box 591, 751 24 Uppsala, Sweden; Science for Life Laboratory, Uppsala University, Box 591, 751 24 Uppsala, Sweden.
  • Liepinsh E; Latvian Institute of Organic Synthesis, Aizkraukles 21, LV-1006 Riga, Latvia.
  • Hobbie SN; Institute of Medical Microbiology, University of Zurich, Gloriastrasse 30, CH-8006 Zurich, Switzerland. Electronic address: sven.hobbie@uzh.ch.
EBioMedicine ; 73: 103652, 2021 Nov.
Article em En | MEDLINE | ID: mdl-34740109
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pielonefrite / Infecções Urinárias / Concentração de Íons de Hidrogênio / Antibacterianos / Nebramicina Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: EBioMedicine Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Suíça País de publicação: Holanda
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pielonefrite / Infecções Urinárias / Concentração de Íons de Hidrogênio / Antibacterianos / Nebramicina Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: EBioMedicine Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Suíça País de publicação: Holanda