Vascular Tumors of Bone: Updates and Diagnostic Pitfall.
Surg Pathol Clin
; 14(4): 645-663, 2021 Dec.
Article
em En
| MEDLINE
| ID: mdl-34742485
ABSTRACT
Vascular tumors of bone can be diagnostically challenging because of their rarity and histologic overlap with diverse mimics. Vascular tumors of bone can be categorized as benign (hemangioma), intermediate-locally aggressive (epithelioid hemangioma), intermediate-rarely metastasizing (pseudomyogenic hemangioendothelioma), and malignant (epithelioid hemangioendothelioma and angiosarcoma). Recurrent genetic alterations have been described, such as FOSB rearrangements in pseudomyogenic hemangioendothelioma and a subset of epithelioid hemangiomas; CAMTA1 or TFE3 rearrangements in epithelioid hemangioendothelioma. This review discusses the clinical, histologic, and molecular features of vascular tumors of bone, along with diagnostic pitfalls and strategies for avoidance.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sarcoma
/
Hemangioendotelioma Epitelioide
/
Neoplasias Vasculares
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Hemangiossarcoma
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Neoplasias de Tecido Vascular
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Child
/
Humans
Idioma:
En
Revista:
Surg Pathol Clin
Ano de publicação:
2021
Tipo de documento:
Article