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An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients.
Li, Jonathan; Lim, Ryan G; Kaye, Julia A; Dardov, Victoria; Coyne, Alyssa N; Wu, Jie; Milani, Pamela; Cheng, Andrew; Thompson, Terri G; Ornelas, Loren; Frank, Aaron; Adam, Miriam; Banuelos, Maria G; Casale, Malcolm; Cox, Veerle; Escalante-Chong, Renan; Daigle, J Gavin; Gomez, Emilda; Hayes, Lindsey; Holewenski, Ronald; Lei, Susan; Lenail, Alex; Lima, Leandro; Mandefro, Berhan; Matlock, Andrea; Panther, Lindsay; Patel-Murray, Natasha Leanna; Pham, Jacqueline; Ramamoorthy, Divya; Sachs, Karen; Shelley, Brandon; Stocksdale, Jennifer; Trost, Hannah; Wilhelm, Mark; Venkatraman, Vidya; Wassie, Brook T; Wyman, Stacia; Yang, Stephanie; Van Eyk, Jennifer E; Lloyd, Thomas E; Finkbeiner, Steven; Fraenkel, Ernest; Rothstein, Jeffrey D; Sareen, Dhruv; Svendsen, Clive N; Thompson, Leslie M.
Afiliação
  • Li J; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Lim RG; UCI MIND, University of California, Irvine, CA 92697, USA.
  • Kaye JA; Center for Systems and Therapeutics and the Taube/Koret Center for Neurodegenerative Disease, Gladstone Institutes, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Dardov V; The Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA.
  • Coyne AN; Advanced Clinical Biosystems Research Institute, The Barbra Streisand Heart Center, The Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Wu J; Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MA 212056, USA.
  • Milani P; Department of Neurology and Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MA 212056, USA.
  • Cheng A; Department of Biological Chemistry, University of California, Irvine, CA 92697, USA.
  • Thompson TG; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Ornelas L; Cellular and Molecular Medicine Program, Johns Hopkins University School of Medicine, Baltimore, MA 212056, USA.
  • Frank A; UCI MIND, University of California, Irvine, CA 92697, USA.
  • Adam M; The Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA.
  • Banuelos MG; The Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA.
  • Casale M; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Cox V; The Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA.
  • Escalante-Chong R; UCI MIND, University of California, Irvine, CA 92697, USA.
  • Daigle JG; Department of Neurobiology and Behavior, University of California, Irvine, CA 92697, USA.
  • Gomez E; Cellular and Molecular Medicine Program, Johns Hopkins University School of Medicine, Baltimore, MA 212056, USA.
  • Hayes L; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Holewenski R; Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MA 212056, USA.
  • Lei S; Department of Neurology and Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MA 212056, USA.
  • Lenail A; The Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA.
  • Lima L; Department of Neurology and Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MA 212056, USA.
  • Mandefro B; Advanced Clinical Biosystems Research Institute, The Barbra Streisand Heart Center, The Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Matlock A; The Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA.
  • Panther L; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Patel-Murray NL; Center for Systems and Therapeutics and the Taube/Koret Center for Neurodegenerative Disease, Gladstone Institutes, University of California, San Francisco, San Francisco, CA 94158, USA.
  • Pham J; The Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA.
  • Ramamoorthy D; Advanced Clinical Biosystems Research Institute, The Barbra Streisand Heart Center, The Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Sachs K; The Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA.
  • Shelley B; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Stocksdale J; Department of Neurology and Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MA 212056, USA.
  • Trost H; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Wilhelm M; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Venkatraman V; The Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA.
  • Wassie BT; UCI MIND, University of California, Irvine, CA 92697, USA.
  • Wyman S; Department of Neurobiology and Behavior, University of California, Irvine, CA 92697, USA.
  • Yang S; The Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048, USA.
  • Van Eyk JE; Advanced Clinical Biosystems Research Institute, The Barbra Streisand Heart Center, The Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Lloyd TE; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Finkbeiner S; Sue and Bill Gross Stem Cell Center, University of California, Irvine, CA 92697, USA.
  • Fraenkel E; Brain Science Institute, Johns Hopkins University School of Medicine, Baltimore, MA 212056, USA.
  • Sareen D; Advanced Clinical Biosystems Research Institute, The Barbra Streisand Heart Center, The Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Svendsen CN; Department of Neurology and Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MA 212056, USA.
  • Thompson LM; Center for Systems and Therapeutics and the Taube/Koret Center for Neurodegenerative Disease, Gladstone Institutes, University of California, San Francisco, San Francisco, CA 94158, USA.
iScience ; 24(11): 103221, 2021 Nov 19.
Article em En | MEDLINE | ID: mdl-34746695

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: IScience Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: IScience Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos