Synthesis of a cyclic tetramer of 3-amino-3-deoxyallose with axially oriented amino groups.
Carbohydr Res
; 511: 108476, 2022 Jan.
Article
em En
| MEDLINE
| ID: mdl-34800752
ABSTRACT
A linear tetramer of ß-(1 â 6)-linked 3-azido-3-deoxy-d-allose containing glycosyl donor and glycosyl acceptor functions in the terminal monosaccharide units was prepared starting from 3-azido-3-deoxy-1,25,6-di-O-isopropylidene-α-d-allofuranose. Cyclization of the linear tetramer under glycosylation conditions afforded the corresponding cyclic tetrasaccharide in 77% yield; its deprotection and reduction of the azido groups resulted in the formation of the cyclic tetramer of 3-amino-3-deoxy-d-allose with axial amino groups, a potential scaffold for the synthesis of tetravalent functional clusters.
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1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Oligossacarídeos
Idioma:
En
Revista:
Carbohydr Res
Ano de publicação:
2022
Tipo de documento:
Article