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Design, Synthesis, biological investigations and molecular interactions of triazole linked tacrine glycoconjugates as Acetylcholinesterase inhibitors with reduced hepatotoxicity.
Kaur Gulati, Harmandeep; Choudhary, Sushil; Kumar, Nitish; Ahmed, Ajaz; Bhagat, Kavita; Vir Singh, Jatinder; Singh, Atamjit; Kumar, Ajay; Singh Bedi, Preet Mohinder; Singh, Harbinder; Mukherjee, Debaraj.
Afiliação
  • Kaur Gulati H; Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, Punjab 143005, India.
  • Choudhary S; PK-PD Toxicology Division, CSIR-IIIM, Jammu 180001, India; Academy of Scientific and Innovative Research (AcSIR-IIIM), Jammu 180001, India.
  • Kumar N; Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, Punjab 143005, India; Drug and Pollution Testing Laboratory, Guru Nanak Dev University, Amritsar, Punjab 143005, India.
  • Ahmed A; Natural Product Chemistry Division, CSIR-IIIM, Jammu 180001, India; Academy of Scientific and Innovative Research (AcSIR-IIIM), Jammu 180001, India.
  • Bhagat K; Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, Punjab 143005, India.
  • Vir Singh J; Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, Punjab 143005, India.
  • Singh A; Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, Punjab 143005, India.
  • Kumar A; PK-PD Toxicology Division, CSIR-IIIM, Jammu 180001, India.
  • Singh Bedi PM; Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, Punjab 143005, India; Drug and Pollution Testing Laboratory, Guru Nanak Dev University, Amritsar, Punjab 143005, India.
  • Singh H; Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, Punjab 143005, India.
  • Mukherjee D; Natural Product Chemistry Division, CSIR-IIIM, Jammu 180001, India; Academy of Scientific and Innovative Research (AcSIR-IIIM), Jammu 180001, India. Electronic address: dmukherjee@iiim.ac.in.
Bioorg Chem ; 118: 105479, 2022 01.
Article em En | MEDLINE | ID: mdl-34801945
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acetilcolinesterase / Tacrina / Triazóis / Glicoconjugados / Desenho de Fármacos / Inibidores da Colinesterase / Antineoplásicos Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Índia País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acetilcolinesterase / Tacrina / Triazóis / Glicoconjugados / Desenho de Fármacos / Inibidores da Colinesterase / Antineoplásicos Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Índia País de publicação: Estados Unidos