Hydrogen/Deuterium Exchange Mass Spectrometry with Integrated Electrochemical Reduction and Microchip-Enabled Deglycosylation for Epitope Mapping of Heavily Glycosylated and Disulfide-Bonded Proteins.

Comamala, Gerard; Krogh, Camilla C; Nielsen, Vibe S; Kutter, Jörg P; Voglmeir, Josef; Rand, Kasper D

Comamala, Gerard; Krogh, Camilla C; Nielsen, Vibe S; Kutter, Jörg P; Voglmeir, Josef; Rand, Kasper D.

Afiliação

Comamala G; Protein Analysis Group, Department of Pharmacy, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.
Krogh CC; Protein Analysis Group, Department of Pharmacy, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.
Nielsen VS; Protein Analysis Group, Department of Pharmacy, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.
Kutter JP; Microscale Analytical Systems Group, Department of Pharmacy, University of Copenhagen, 2100 Copenhagen, Denmark.
Voglmeir J; Glycomics and Glycan Bioengineering Research Center (GGBRC), College of Food Science and Technology, Nanjing Agricultural University, Nanjing 210095, China.
Rand KD; Protein Analysis Group, Department of Pharmacy, University of Copenhagen, Universitetsparken 2, 2100 Copenhagen, Denmark.

Anal Chem ; 93(49): 16330-16340, 2021 12 14.

Article em En | MEDLINE | ID: mdl-34843209

Assuntos

Glicoproteínas; Espectrometria de Massa com Troca Hidrogênio-Deutério; Deutério; Dissulfetos; Mapeamento de Epitopos

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glicoproteínas / Espectrometria de Massa com Troca Hidrogênio-Deutério Idioma: En Revista: Anal Chem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Dinamarca País de publicação: Estados Unidos

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