Fluid intake and blood pressure in children: the Salus per Aquam project.
J Hypertens
; 40(1): 171-179, 2022 01 01.
Article
em En
| MEDLINE
| ID: mdl-34857709
ABSTRACT
BACKGROUND:
Sodium intake is known to contribute to the development of hypertension, thus intake reduction is a cornerstone in the prevention and management of hypertension. The increase in renal sodium excretion might represent a further potential preventive and/or therapeutic opportunity.OBJECTIVE:
To explore the working hypothesis that an increased fluid intake can improve renal sodium handling towards a decrease in blood pressure.METHODS:
The SPA Project is a multicenter, observational, cross-sectional, cohort study investigating healthy children, aged 5-8âyears as to sodium and fluid intake by means of urinary sodium and creatinine from multiple samples taken in different days in order to characterize them in lower/higher sodium and lower/higher fluid intake. Both SBP and DBP (by multiple office blood pressure measurements) were used as outcome measures.RESULTS:
Three hundred and thirty-nine healthy, nonoverweight children (51.6% boys) with a median age of 5.7âyears old (IQR 5.3-6.2) participated in the study but only 223 could be analyzed. Among children with higher sodium intake, those introducing more fluids, showed a significantly lower blood pressure (both systolic and diastolic) compared with those with lower fluid intake systolic 86.0â±â8.5 vs. 90.0â±â8.1âmmHg; Pâ=â0.014 and diastolic 53.8â±â4.9 vs. 58.6â±â6.6âmmHg; Pâ<â0.0001.CONCLUSION:
An increased fluid intake is associated with a reduced blood pressure possibly by increasing renal sodium excretion. We speculate that this simple, highly acceptable, inexpensive, and harmless measure might have a role in preventing and/or minimizing the epidemics of hypertension and of its related morbidities both in children and in adults.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hipertensão
Tipo de estudo:
Clinical_trials
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Etiology_studies
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Incidence_studies
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Observational_studies
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Prevalence_studies
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Risk_factors_studies
Limite:
Adult
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Child
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Child, preschool
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Female
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Humans
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Male
Idioma:
En
Revista:
J Hypertens
Ano de publicação:
2022
Tipo de documento:
Article