[Effects of oral manganese supplementation with different compounds on the manganese whole blood and serum concentrations of broodmares and their suckling foals]. / Effekte einer oralen Mangansupplementierung mit unterschiedlichen Verbindungen auf die Mangankonzentrationen in Vollblut und Serum von Stuten und Saugfohlen.
Tierarztl Prax Ausg G Grosstiere Nutztiere
; 49(6): 392-402, 2021 Dec.
Article
em De
| MEDLINE
| ID: mdl-34861732
ABSTRACT
OBJECTIVE:
This study aimed to examine the effects of an oral supplementation on manganese (Mn) concentrations in the blood of lactating warm-blood broodmares. Furthermore, the potential relationship between Mn supply of the lactating mare and its suckling foal was investigated. MATERIAL ANDMETHODS:
During the 90-day trial, lactating mares were divided into 3 groups and daily received a daily dose of either a placebo (nâ =â 11) or a Mn supplement of 560â mg Mn as Mn sulfate (nâ =â 11) or Mn chelate (nâ =â 11) in addition to the Mn intake from the basal ration (hay ad libitum, total mixed ration Mn intake ~ 100â mg/kg dry matter). Blood samples were taken from the mares and their foals in 14-day intervals. The Mn determination in serum and whole blood as well as in the mare's milk was carried out by means of mass spectrometry with inductively coupled plasma. The Mn analysis in representative feed samples was performed by means of atomic absorption spectrometry. Data were assessed using the software IBM SPSS Statistics 27 (IBM Deutschland GmbH, Ehningen).RESULTS:
During the trial period, the mares showed Mn concentrations 10-fold higher in whole blood (median 15.6â µg/l; 25-75 percentile 12.8-18.5â µg/l) than in serum (median 1.54â µg/l; 25-75 percentile 1.20-1.90â µg/l). The foals had Mn whole-blood concentrations 16.4-fold higher (median 21.3â µg/l; 25-75 percentile 16.7-28.1â µg/l) compared to their serum (median 1.50â µg/l; 25-75 percentile 1.30-1.70â µg/l). The Mn whole-blood levels of the foals corresponded to 1.6-fold the Mn concentration of their dams. The milk contained a median Mn concentration of 0.012â mg/kg fresh matter. Mn supplementation had no effect on the Mn blood levels of mares and their foals. CONCLUSION AND CLINICAL RELEVANCE Blood Mn concentrations were not affected by the Mn supplementation. However, the Mn levels differed significantly between serum and whole blood. In addition, the Mn concentrations in whole blood of suckling foals were higher compared to their dams, although the Mn concentrations in the mare's milk were low regardless of Mn supplementation. Due to the low Mn content in milk, early Mn supply, preferably by forages, is necessary to ensure that the foals are supplied with Mn according to their requirement.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Lactação
/
Manganês
Limite:
Animals
Idioma:
De
Revista:
Tierarztl Prax Ausg G Grosstiere Nutztiere
Assunto da revista:
MEDICINA VETERINARIA
Ano de publicação:
2021
Tipo de documento:
Article