Hsa_circ_0001879 promotes the progression of atherosclerosis by regulating the proliferation and migration of oxidation of low density lipoprotein (ox-LDL)-induced vascular endothelial cells via the miR-6873-5p-HDAC9 axis.

Li, Feifei; Chen, Yahui; He, Zhiling; Wang, Chuangchang; Wang, Xiaoli; Pan, Guangming; Peng, Jiang Yang; Chen, Qiuxiong; Wang, Xia

Li, Feifei; Chen, Yahui; He, Zhiling; Wang, Chuangchang; Wang, Xiaoli; Pan, Guangming; Peng, Jiang Yang; Chen, Qiuxiong; Wang, Xia.

Afiliação

Li F; Department of Cardiology, Guangdong Provincial Hospital of Traditional Chinese Medicine; The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Chen Y; Department of Cardiology, Guangdong Provincial Hospital of Traditional Chinese Medicine; The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
He Z; Department of Cardiology, Guangdong Provincial Hospital of Traditional Chinese Medicine; The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Wang C; The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Wang X; Department of Cardiology, Guangdong Provincial Hospital of Traditional Chinese Medicine; The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Pan G; Department of Cardiology, Guangdong Provincial Hospital of Traditional Chinese Medicine; The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Peng JY; Department of Cardiology, Guangdong Provincial Hospital of Traditional Chinese Medicine; The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Chen Q; The Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Wang X; Department of Cardiology, Guangdong Provincial Hospital of Traditional Chinese Medicine; The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.

Bioengineered ; 12(2): 10420-10429, 2021 12.

Article em En | MEDLINE | ID: mdl-34872444

Assuntos

Aterosclerose/genética; Aterosclerose/patologia; Movimento Celular; Histona Desacetilases/metabolismo; Células Endoteliais da Veia Umbilical Humana/patologia; Lipoproteínas LDL/farmacologia; MicroRNAs/metabolismo; RNA Circular/metabolismo; Proteínas Repressoras/metabolismo; Sequência de Bases; Biomarcadores/metabolismo; Movimento Celular/efeitos dos fármacos; Movimento Celular/genética; Proliferação de Células/efeitos dos fármacos; Progressão da Doença; Transição Epitelial-Mesenquimal/efeitos dos fármacos; Transição Epitelial-Mesenquimal/genética; Células Endoteliais da Veia Umbilical Humana/efeitos dos fármacos; Células Endoteliais da Veia Umbilical Humana/metabolismo; Humanos; MicroRNAs/genética; Proteólise/efeitos dos fármacos; RNA Circular/genética; Regulação para Cima/efeitos dos fármacos; Regulação para Cima/genética

Palavras-chave

Atherosclerosis; HDAC9; Hsa_circ_0001879; ceRNA; circRNA; miR-6873-5p

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Repressoras / Movimento Celular / MicroRNAs / Aterosclerose / Células Endoteliais da Veia Umbilical Humana / RNA Circular / Histona Desacetilases / Lipoproteínas LDL Limite: Humans Idioma: En Revista: Bioengineered Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos

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