Comparison of gold and PEDOT:PSS contacts for high-resolution gastric electrical mapping using flexible printed circuit arrays.
Annu Int Conf IEEE Eng Med Biol Soc
; 2021: 6937-6940, 2021 11.
Article
em En
| MEDLINE
| ID: mdl-34892699
ABSTRACT
Motility of the stomach is governed by an electrophysiological event termed gastric slow waves. High-resolution (HR) bioelectrical mapping involves placing array of electrodes over the surface of the stomach to record gastric slow waves. Conductive polymer materials have recently been applied to great effect in cardiology and neurophysiology due to its compliant and biocompatible properties. The aim of this study was to quantify the performance of poly(3,4-ethylenedioxythiophene) doped with poly(styrenesulfonate) (PEDOTPSS) deposited on a flexible print circuit electrode array for gastric slow wave HR mapping. The Au electrodes were coated with PEDOTPSS at 1 V and different levels of charges (0.3-1.2 mC). HR mapping alongside standard Au electrodes was performed in three anesthetized pigs. Overall, the PEDOTPSS electrodes detected both antegrade and retrograde slow wave propagations, with comparable frequency, velocity and signal-to-noise ratio to the Au electrodes. Differences between the two electrodes were noted in terms of amplitude and downstroke gradient. The findings of this study will inform designs of future stretchable and implantable HR mapping electrode arrays for gastrointestinal recording and stimulation therapies.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Compostos Bicíclicos Heterocíclicos com Pontes
/
Ouro
Limite:
Animals
Idioma:
En
Revista:
Annu Int Conf IEEE Eng Med Biol Soc
Ano de publicação:
2021
Tipo de documento:
Article
País de publicação:
EEUU
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ESTADOS UNIDOS
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ESTADOS UNIDOS DA AMERICA
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EUA
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UNITED STATES
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UNITED STATES OF AMERICA
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US
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USA