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Discovery of N-(1,3,4-thiadiazol-2-yl)benzamide derivatives containing a 6,7-methoxyquinoline structure as novel EGFR/HER-2 dual-target inhibitors against cancer growth and angiogenesis.
Li, Xin-Yang; Wang, De-Pu; Li, Shuai; Xue, Wen-Han; Qian, Xin-Hua; Liu, Kai-Li; Li, Yu-Heng; Lin, Qi-Qi; Dong, Gang; Meng, Fan-Hao; Jian, Ling-Yan.
Afiliação
  • Li XY; Department of Pharmacy, Shengjing Hospital of China Medical University, Shenyang 110004, PR China; School of Pharmacy, China Medical University, Shenyang 110122, PR China.
  • Wang DP; Department of Pharmacy, Shengjing Hospital of China Medical University, Shenyang 110004, PR China; School of Pharmacy, China Medical University, Shenyang 110122, PR China.
  • Li S; Department of Pharmacy, Shengjing Hospital of China Medical University, Shenyang 110004, PR China; School of Pharmacy, China Medical University, Shenyang 110122, PR China.
  • Xue WH; School of Pharmacy, China Medical University, Shenyang 110122, PR China.
  • Qian XH; School of Pharmacy, China Medical University, Shenyang 110122, PR China.
  • Liu KL; School of Pharmacy, China Medical University, Shenyang 110122, PR China.
  • Li YH; School of Pharmacy, China Medical University, Shenyang 110122, PR China.
  • Lin QQ; School of Pharmacy, China Medical University, Shenyang 110122, PR China.
  • Dong G; School of Pharmacy, China Medical University, Shenyang 110122, PR China.
  • Meng FH; School of Pharmacy, China Medical University, Shenyang 110122, PR China.
  • Jian LY; Department of Pharmacy, Shengjing Hospital of China Medical University, Shenyang 110004, PR China. Electronic address: jianly@sj-hospital.org.
Bioorg Chem ; 119: 105469, 2022 02.
Article em En | MEDLINE | ID: mdl-34915285
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiadiazóis / Benzamidas / Inibidores de Proteínas Quinases / Descoberta de Drogas / Neovascularização Patológica / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2022 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiadiazóis / Benzamidas / Inibidores de Proteínas Quinases / Descoberta de Drogas / Neovascularização Patológica / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2022 Tipo de documento: Article País de publicação: Estados Unidos