Three new compounds from the dried root bark of Wikstroemia indica and their cytotoxicity against HeLa cells.
Nat Prod Res
; 36(21): 5476-5483, 2022 Nov.
Article
em En
| MEDLINE
| ID: mdl-34965788
ABSTRACT
Three new compounds (1-3) and twelve known compounds (4-15) were isolated from the n-butanol extraction of the 70% ethanol extract of the dried root barks of Wikstroemia indica. The structures of new compounds were identified by chemical evidence and extensive analysis of spectroscopic data (HR-ESI-MS, 1 D and 2 D NMR) and ECD calculations. All isolated compounds were evaluated for their cytotoxicity against HeLa cells using MTT assay and the results showed that daphnoretin (compound 5) owned the highest cytotoxicity against HeLa cells (IC50=28.89 µmol/L).
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Wikstroemia
Limite:
Humans
Idioma:
En
Revista:
Nat Prod Res
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
China