lncRNA HITT inhibits metastasis by attenuating Rab5-mediated endocytosis in lung adenocarcinoma.

Wang, Xingwen; Zheng, Shanliang; Yang, Fan; Zhang, Wenxin; Zhao, Dong; Xue, Xuting; Lin, Qingyu; He, Yunfei; Hu, Guohong; Hu, Ying

Wang, Xingwen; Zheng, Shanliang; Yang, Fan; Zhang, Wenxin; Zhao, Dong; Xue, Xuting; Lin, Qingyu; He, Yunfei; Hu, Guohong; Hu, Ying.

Afiliação

Wang X; School of Life Science and Technology, Harbin Institute of Technology, Harbin, Heilongjiang Province 150001, China.
Zheng S; School of Life Science and Technology, Harbin Institute of Technology, Harbin, Heilongjiang Province 150001, China.
Yang F; School of Life Science and Technology, Harbin Institute of Technology, Harbin, Heilongjiang Province 150001, China.
Zhang W; School of Life Science and Technology, Harbin Institute of Technology, Harbin, Heilongjiang Province 150001, China.
Zhao D; School of Life Science and Technology, Harbin Institute of Technology, Harbin, Heilongjiang Province 150001, China.
Xue X; School of Life Science and Technology, Harbin Institute of Technology, Harbin, Heilongjiang Province 150001, China.
Lin Q; School of Life Science and Technology, Harbin Institute of Technology, Harbin, Heilongjiang Province 150001, China.
He Y; Shanghai Institute of Nutrition and Health, University of Chinese Academy of Science, 320 Yuyang Road, Shanghai 200031, China.
Hu G; Shanghai Institute of Nutrition and Health, University of Chinese Academy of Science, 320 Yuyang Road, Shanghai 200031, China.
Hu Y; School of Life Science and Technology, Harbin Institute of Technology, Harbin, Heilongjiang Province 150001, China; Shenzhen Graduate School of Harbin Institute of Technology, Shenzhen 518055, China. Electronic address: huying@hit.edu.cn.

Mol Ther ; 30(3): 1071-1088, 2022 03 02.

Article em En | MEDLINE | ID: mdl-35017116

Assuntos

Adenocarcinoma; RNA Longo não Codificante; Endocitose/genética; Humanos; Integrina beta1/genética; Integrina beta1/metabolismo; Pulmão/metabolismo; RNA Longo não Codificante/genética; Proteínas rab5 de Ligação ao GTP/genética; Proteínas rab5 de Ligação ao GTP/metabolismo

Palavras-chave

HITT; Rab5; cancer metastasis; endocytosis; ß1-integrin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Adenocarcinoma / RNA Longo não Codificante Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Mol Ther Assunto da revista: BIOLOGIA MOLECULAR / TERAPEUTICA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos

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