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An adapted passive model of anti-MPO dependent crescentic glomerulonephritis reveals matrix dysregulation and is amenable to modulation by CXCR4 inhibition.
Fayçal, Chérine Abou; Oszwald, Andre; Feilen, Tobias; Cosenza-Contreras, Miguel; Schilling, Oliver; Loustau, Thomas; Steinbach, Fanny; Schachner, Helga; Langer, Brigitte; Heeringa, Peter; Rees, Andrew J; Orend, Gertraud; Kain, Renate.
Afiliação
  • Fayçal CA; INSERM U1109, The Tumor Microenvironment Laboratory, Strasbourg, France; Université Strasbourg, Hopital Civil, Institut d'Hématologie et d'Immunologie, Strasbourg, France; Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, France; These authors (CAF and AO) contributed equally
  • Oszwald A; Department of Pathology, Medical University of Vienna, Vienna, Austria; These authors (CAF and AO) contributed equally to this work.
  • Feilen T; Institute of Surgical Pathology, University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany; Faculty of Biology, University of Freiburg, Schänzlestraße 1, 79104 Freiburg, Germany.
  • Cosenza-Contreras M; Institute of Surgical Pathology, University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany; Faculty of Biology, University of Freiburg, Schänzlestraße 1, 79104 Freiburg, Germany.
  • Schilling O; Institute of Surgical Pathology, University Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany; German Cancer Consortium (DKTK) and Cancer Research Center (DKFZ), Hugstetter Straße 55, 79106 Freiburg, Germany.
  • Loustau T; INSERM U1109, The Tumor Microenvironment Laboratory, Strasbourg, France; Université Strasbourg, Hopital Civil, Institut d'Hématologie et d'Immunologie, Strasbourg, France; Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, France.
  • Steinbach F; INSERM U1109, The Tumor Microenvironment Laboratory, Strasbourg, France; Université Strasbourg, Hopital Civil, Institut d'Hématologie et d'Immunologie, Strasbourg, France; Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, France.
  • Schachner H; Department of Pathology, Medical University of Vienna, Vienna, Austria.
  • Langer B; Department of Pathology, Medical University of Vienna, Vienna, Austria.
  • Heeringa P; Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
  • Rees AJ; Department of Pathology, Medical University of Vienna, Vienna, Austria.
  • Orend G; INSERM U1109, The Tumor Microenvironment Laboratory, Strasbourg, France; Université Strasbourg, Hopital Civil, Institut d'Hématologie et d'Immunologie, Strasbourg, France; Fédération de Médecine Translationnelle de Strasbourg (FMTS), Strasbourg, France. Electronic address: gertraud.orend@inserm.fr.
  • Kain R; Department of Pathology, Medical University of Vienna, Vienna, Austria. Electronic address: renate.kain@meduniwein.ac.at.
Matrix Biol ; 106: 12-33, 2022 02.
Article em En | MEDLINE | ID: mdl-35032611
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores CXCR4 / Vasculite Associada a Anticorpo Anticitoplasma de Neutrófilos / Glomerulonefrite Limite: Animals / Humans Idioma: En Revista: Matrix Biol Assunto da revista: BIOLOGIA MOLECULAR / BIOQUIMICA Ano de publicação: 2022 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores CXCR4 / Vasculite Associada a Anticorpo Anticitoplasma de Neutrófilos / Glomerulonefrite Limite: Animals / Humans Idioma: En Revista: Matrix Biol Assunto da revista: BIOLOGIA MOLECULAR / BIOQUIMICA Ano de publicação: 2022 Tipo de documento: Article