Your browser doesn't support javascript.
loading
Squidpy: a scalable framework for spatial omics analysis.
Palla, Giovanni; Spitzer, Hannah; Klein, Michal; Fischer, David; Schaar, Anna Christina; Kuemmerle, Louis Benedikt; Rybakov, Sergei; Ibarra, Ignacio L; Holmberg, Olle; Virshup, Isaac; Lotfollahi, Mohammad; Richter, Sabrina; Theis, Fabian J.
Afiliação
  • Palla G; Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.
  • Spitzer H; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany.
  • Klein M; Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.
  • Fischer D; Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.
  • Schaar AC; Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.
  • Kuemmerle LB; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany.
  • Rybakov S; Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.
  • Ibarra IL; TUM School of Life Sciences Weihenstephan, Technical University of Munich, Munich, Germany.
  • Holmberg O; Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.
  • Virshup I; Institute for Tissue Engineering and Regenerative Medicine (iTERM), Helmholtz Center Munich, Munich, Germany.
  • Lotfollahi M; Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.
  • Richter S; Department of Mathematics, Technical University of Munich, Munich, Germany.
  • Theis FJ; Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.
Nat Methods ; 19(2): 171-178, 2022 02.
Article em En | MEDLINE | ID: mdl-35102346
Spatial omics data are advancing the study of tissue organization and cellular communication at an unprecedented scale. Flexible tools are required to store, integrate and visualize the large diversity of spatial omics data. Here, we present Squidpy, a Python framework that brings together tools from omics and image analysis to enable scalable description of spatial molecular data, such as transcriptome or multivariate proteins. Squidpy provides efficient infrastructure and numerous analysis methods that allow to efficiently store, manipulate and interactively visualize spatial omics data. Squidpy is extensible and can be interfaced with a variety of already existing libraries for the scalable analysis of spatial omics data.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Software / Biologia Computacional / Perfilação da Expressão Gênica / Proteômica Limite: Animals / Humans Idioma: En Revista: Nat Methods Assunto da revista: TECNICAS E PROCEDIMENTOS DE LABORATORIO Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Software / Biologia Computacional / Perfilação da Expressão Gênica / Proteômica Limite: Animals / Humans Idioma: En Revista: Nat Methods Assunto da revista: TECNICAS E PROCEDIMENTOS DE LABORATORIO Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Estados Unidos