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Cathepsin D as a potential therapeutic target to enhance anticancer drug-induced apoptosis via RNF183-mediated destabilization of Bcl-xL in cancer cells.
Seo, Seung Un; Woo, Seon Min; Im, Seung-Soon; Jang, Younghoon; Han, Eugene; Kim, Sang Hyun; Lee, Hongchan; Lee, Hyun-Shik; Nam, Ju-Ock; Gabrielson, Edward; Min, Kyoung-Jin; Kwon, Taeg Kyu.
Afiliação
  • Seo SU; Department of Immunology, School of Medicine, Keimyung University, Daegu, 42601, South Korea.
  • Woo SM; Department of Immunology, School of Medicine, Keimyung University, Daegu, 42601, South Korea.
  • Im SS; Department of Physiology, School of Medicine, Keimyung University, Daegu, 42601, South Korea.
  • Jang Y; Department of Biology and Chemistry, Changwon National University, Changwon, 51140, South Korea.
  • Han E; Department of Internal Medicine, School of Medicine, Keimyung University, Daegu, 42601, South Korea.
  • Kim SH; Department of Pharmacology, School of Medicine, Kyungpook National University, Daegu, 41566, South Korea.
  • Lee H; BK21 FOUR KNU Creative BioResearch Group, School of Life Sciences, Kyungpook National University, Daegu, 41566, South Korea.
  • Lee HS; BK21 FOUR KNU Creative BioResearch Group, School of Life Sciences, Kyungpook National University, Daegu, 41566, South Korea.
  • Nam JO; Department of Food Science and Biotechnology, Kyungpook National University, Daegu, 41566, South Korea.
  • Gabrielson E; Department of Pathology, Johns Hopkins University School of Medicine and the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD, 21231, USA.
  • Min KJ; Department of Immunology, School of Medicine, Keimyung University, Daegu, 42601, South Korea. kjmin@dgmif.re.kr.
  • Kwon TK; New Drug Development Center, Daegu-Gyeongbuk Medical Innovation Foundation (DGMIF), Daegu, 41061, South Korea. kjmin@dgmif.re.kr.
Cell Death Dis ; 13(2): 115, 2022 02 04.
Article em En | MEDLINE | ID: mdl-35121737

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma de Células Renais / Catepsina D / Ubiquitina-Proteína Ligases / Neoplasias Renais / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cell Death Dis Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Coréia do Sul País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma de Células Renais / Catepsina D / Ubiquitina-Proteína Ligases / Neoplasias Renais / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cell Death Dis Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Coréia do Sul País de publicação: Reino Unido