Novel extended IVIVC combined with DoE to predict pharmacokinetics from formulation compositions.

Lim, Jun Young; Kim, Tae Hwan; Song, Chang Ho; Kim, Do-Hyung; Shin, Beom Soo; Shin, Soyoung

Lim, Jun Young; Kim, Tae Hwan; Song, Chang Ho; Kim, Do-Hyung; Shin, Beom Soo; Shin, Soyoung.

Afiliação

Lim JY; School of Pharmacy, Sungkyunkwan University, 2066 Seobu-ro, Jangan-gu, Suwon, Gyeonggi 16419, Republic of Korea.
Kim TH; College of Pharmacy, Daegu Catholic University, 13-13 Hayang-ro, Hayang-eup, Gyeongsan, Gyeongbuk 38430, Republic of Korea.
Song CH; School of Pharmacy, Sungkyunkwan University, 2066 Seobu-ro, Jangan-gu, Suwon, Gyeonggi 16419, Republic of Korea.
Kim DH; KNOTUS Co., Ltd. Research Center, Guri, Gyeonggi 11910, Republic of Korea.
Shin BS; School of Pharmacy, Sungkyunkwan University, 2066 Seobu-ro, Jangan-gu, Suwon, Gyeonggi 16419, Republic of Korea. Electronic address: bsshin@skku.edu.
Shin S; College of Pharmacy, Wonkwang University, 460 Iksan-daero, Iksan, Jeonbuk 54538, Republic of Korea. Electronic address: shins@wku.ac.kr.

J Control Release ; 343: 443-456, 2022 03.

Article em En | MEDLINE | ID: mdl-35124130

Assuntos

Cetoprofeno; Animais; Preparações de Ação Retardada/farmacocinética; Cães; Liberação Controlada de Fármacos; Solubilidade; Comprimidos

Palavras-chave

Design of experiment; In vitro-in vivo correlation; Ketoprofen; Pharmacokinetics; Sustained-release

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cetoprofeno Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: J Control Release Assunto da revista: FARMACOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de publicação: Holanda

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