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Systematic review and meta-analysis of cognitive impairment in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS).
Aoun Sebaiti, Mehdi; Hainselin, Mathieu; Gounden, Yannick; Sirbu, Carmen Adella; Sekulic, Slobodan; Lorusso, Lorenzo; Nacul, Luis; Authier, François Jérôme.
Afiliação
  • Aoun Sebaiti M; Neurology Department, Henri Mondor University Hospital, APHP, Créteil, France.
  • Hainselin M; INSERM U955-Team Relaix, Faculty of Health, Paris Est-Creteil University, Créteil, France.
  • Gounden Y; CRP-CPO, UR UPJV 7273, Université de Picardie Jules Verne, Amiens, France.
  • Sirbu CA; CRP-CPO, UR UPJV 7273, Université de Picardie Jules Verne, Amiens, France.
  • Sekulic S; CRP-CPO, UR UPJV 7273, Université de Picardie Jules Verne, Amiens, France.
  • Lorusso L; Central Military Emergency University Hospital, Titu Maiorescu University, Bucharest, Romania.
  • Nacul L; European Network On ME/CFS (EUROMENE), London, UK.
  • Authier FJ; European Network On ME/CFS (EUROMENE), London, UK.
Sci Rep ; 12(1): 2157, 2022 02 09.
Article em En | MEDLINE | ID: mdl-35140252
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is commonly associated with cognitive complaints. To bring out the neuropsychological symptomatology inherent to ME/CFS, we conducted a systematic review according to PRISMA and MOOSE guidelines of the literature through the analysis of 764 studies published between 1988 and 2019 by using PubMed Central website and Clarivate analytics platform. We performed a meta-analysis to delineate an idea of the neuropsychological profile inherent in ME/CFS. The clinical picture typically affects visuo-spatial immediate memory (g = - 0.55, p = 0.007), reading speed (g = - 0.82, p = 0.0001) and graphics gesture (g = - 0.59, p = 0.0001). Analysis also revealed difficulties in several processes inherent in episodic verbal memory (storage, retrieval, recognition) and visual memory (recovery) and a low efficiency in attentional abilities. Executive functions seemed to be little or not affected and instrumental functions appeared constantly preserved. With regard to the complexity and heterogeneity of the cognitive phenotype, it turns out that determining a sound clinical picture of ME/CFS cognitive profile must go through a neuropsychological examination allowing a complete evaluation integrating the notion of agreement between the choice and the number of tests and the complexity intrinsic to the pathology.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndrome de Fadiga Crônica / Disfunção Cognitiva Tipo de estudo: Diagnostic_studies / Guideline / Systematic_reviews Limite: Adult / Female / Humans / Male Idioma: En Revista: Sci Rep Ano de publicação: 2022 Tipo de documento: Article País de afiliação: França País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndrome de Fadiga Crônica / Disfunção Cognitiva Tipo de estudo: Diagnostic_studies / Guideline / Systematic_reviews Limite: Adult / Female / Humans / Male Idioma: En Revista: Sci Rep Ano de publicação: 2022 Tipo de documento: Article País de afiliação: França País de publicação: Reino Unido