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A novel phage display based platform for exosome diversity characterization.
Maisano, Domenico; Mimmi, Selena; Dattilo, Vincenzo; Marino, Fabiola; Gentile, Massimo; Vecchio, Eleonora; Fiume, Giuseppe; Nisticò, Nancy; Aloisio, Annamaria; de Santo, Maria Penelope; Desiderio, Giovanni; Musolino, Vincenzo; Nucera, Saverio; Sbrana, Francesca; Andò, Sebastiano; Ferrero, Simone; Morandi, Andrea; Bertoni, Francesco; Quinto, Ileana; Iaccino, Enrico.
Afiliação
  • Maisano D; Department of Experimental and Clinical Medicine, University "Magna Graecia of Catanzaro", Catanzaro, Italy. iaccino@unicz.it.
  • Mimmi S; Department of Experimental and Clinical Medicine, University "Magna Graecia of Catanzaro", Catanzaro, Italy. iaccino@unicz.it.
  • Dattilo V; Genetics Units, IRCCS Centro San Giovanni di Dio Fatebenefratelli, Brescia, Italy.
  • Marino F; Department of Experimental and Clinical Medicine, University "Magna Graecia of Catanzaro", Catanzaro, Italy. iaccino@unicz.it.
  • Gentile M; Hematology Unit, Annunziata Hospital, Cosenza, Italy.
  • Vecchio E; Department of Experimental and Clinical Medicine, University "Magna Graecia of Catanzaro", Catanzaro, Italy. iaccino@unicz.it.
  • Fiume G; Department of Experimental and Clinical Medicine, University "Magna Graecia of Catanzaro", Catanzaro, Italy. iaccino@unicz.it.
  • Nisticò N; Department of Experimental and Clinical Medicine, University "Magna Graecia of Catanzaro", Catanzaro, Italy. iaccino@unicz.it.
  • Aloisio A; Department of Experimental and Clinical Medicine, University "Magna Graecia of Catanzaro", Catanzaro, Italy. iaccino@unicz.it.
  • de Santo MP; CNR/Nanotec, Physics Department, University of Calabria, Rende, CS, Italy.
  • Desiderio G; CNR/Nanotec, Physics Department, University of Calabria, Rende, CS, Italy.
  • Musolino V; IRC-FSH Department of Health Sciences, University "Magna Græcia" of Catanzaro, Catanzaro, Italy.
  • Nucera S; IRC-FSH Department of Health Sciences, University "Magna Græcia" of Catanzaro, Catanzaro, Italy.
  • Sbrana F; Schaefer SEE srl, Via Luigi Einaudi 23, Rovigo, RO, Italy.
  • Andò S; Health Center, University of Calabria, Rende, CS, Italy. sebastiano.ando@unical.it.
  • Ferrero S; Division of Hematology, Department of Molecular Biotechnologies and Health Sciences, University of Torino, Turin, Italy.
  • Morandi A; Department of Experimental and Clinical Biomedical Sciences, University of Florence, Florence, Italy.
  • Bertoni F; IOR, Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland.
  • Quinto I; Department of Experimental and Clinical Medicine, University "Magna Graecia of Catanzaro", Catanzaro, Italy. iaccino@unicz.it.
  • Iaccino E; Department of Experimental and Clinical Medicine, University "Magna Graecia of Catanzaro", Catanzaro, Italy. iaccino@unicz.it.
Nanoscale ; 14(8): 2998-3003, 2022 Feb 24.
Article em En | MEDLINE | ID: mdl-35141731
ABSTRACT
We present an innovative approach allowing the identification, isolation, and molecular characterization of disease-related exosomes based on their different antigenic reactivities. The designed strategy could be immediately translated into any disease in which exosomes are involved. The identification of specific markers and their subsequent association with exosome subtypes, together with the possibility to engineer target-guided exosome-like particles, could represent the key for the effective adoption of exosomes in clinical practice.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bacteriófagos / Exossomos Idioma: En Revista: Nanoscale Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Itália

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bacteriófagos / Exossomos Idioma: En Revista: Nanoscale Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Itália