A new butenolide with antifungal activity from solid co-cultivation of Irpex lacteus and Nigrospora oryzae.
Nat Prod Res
; 37(13): 2243-2247, 2023 Jul.
Article
em En
| MEDLINE
| ID: mdl-35147448
ABSTRACT
A new antifungal butenolide irperide (1) along with five known compounds were isolated from the co-culture of endophyte Irpex lacteus and pathogenic Nigrospora oryzae. The structure of 1, including the absolute configuration, was elucidated by analysis of NMR, HR-ESI-MS data and ECD spectra. Compounds 1, 4 and 6 exhibited significant antifungal activity against Aspergillus fumigatus, with MIC values of 1, 2 and 1 µg/mL, respectively.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ascomicetos
/
Antifúngicos
Idioma:
En
Revista:
Nat Prod Res
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
China