Local Accumulation of Lymphocytes in the Intima of Human Aorta Is Associated with Giant Multinucleated Endothelial Cells: Possible Explanation for Mosaicism of Atherosclerosis.

Nikiforov, Nikita G; Zlenko, Dmitry V; Orekhova, Varvara A; Melnichenko, Alexandra A; Orekhov, Alexander N

Nikiforov, Nikita G; Zlenko, Dmitry V; Orekhova, Varvara A; Melnichenko, Alexandra A; Orekhov, Alexander N.

Afiliação

Nikiforov NG; Laboratory of Medical Genetics, Institute of Experimental Cardiology, National Medical Research Center of Cardiology, 121552 Moscow, Russia.
Zlenko DV; Center for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Orekhova VA; Laboratory of Angiopathology, Institute of General Pathology and Pathophysiology, 125315 Moscow, Russia.
Melnichenko AA; N.N. Semenov Federal Research Center for Chemical Physics RAS, 119991 Moscow, Russia.
Orekhov AN; Faculty of Biology, M.V. Lomonosov Moscow State University, 119991 Moscow, Russia.

Int J Mol Sci ; 23(3)2022 Jan 19.

Article em En | MEDLINE | ID: mdl-35162983

Assuntos

Aterosclerose; Células Endoteliais; Adulto; Aorta/patologia; Aterosclerose/patologia; Células Endoteliais/patologia; Endotélio Vascular/patologia; Humanos; Lipoproteínas LDL; Linfócitos/patologia; Pessoa de Meia-Idade; Mosaicismo; Adulto Jovem

Palavras-chave

LDL; aortic intima; atherosclerosis; giant multinuclear endothelial cells; leukocytes; mosaicism

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Endoteliais / Aterosclerose Tipo de estudo: Risk_factors_studies Limite: Adult / Humans / Middle aged Idioma: En Revista: Int J Mol Sci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Federação Russa

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