Cucurbitacin B inhibits TGF-ß1-induced epithelial-mesenchymal transition (EMT) in NSCLC through regulating ROS and PI3K/Akt/mTOR pathways.

Yuan, Renyikun; Fan, Qiumei; Liang, Xiaowei; Han, Shan; He, Jia; Wang, Qin-Qin; Gao, Hongwei; Feng, Yulin; Yang, Shilin

Yuan, Renyikun; Fan, Qiumei; Liang, Xiaowei; Han, Shan; He, Jia; Wang, Qin-Qin; Gao, Hongwei; Feng, Yulin; Yang, Shilin.

Afiliação

Yuan R; College of Pharmacy, Jiangxi University of Traditional Chinese Medicine, Nanchang, 330004, China.
Fan Q; College of Pharmacy, Guangxi University of Chinese Medicine, Nanning, 530000, China.
Liang X; College of Pharmacy, Guangxi University of Chinese Medicine, Nanning, 530000, China.
Han S; College of Pharmacy, Guangxi University of Chinese Medicine, Nanning, 530000, China.
He J; College of Pharmacy, Jiangxi University of Traditional Chinese Medicine, Nanchang, 330004, China.
Wang QQ; College of Pharmacy, Guangxi University of Chinese Medicine, Nanning, 530000, China.
Gao H; College of Pharmacy, Jiangxi University of Traditional Chinese Medicine, Nanchang, 330004, China.
Feng Y; College of Pharmacy, Guangxi University of Chinese Medicine, Nanning, 530000, China.
Yang S; College of Pharmacy, Guangxi University of Chinese Medicine, Nanning, 530000, China.

Chin Med ; 17(1): 24, 2022 Feb 19.

Article em En | MEDLINE | ID: mdl-35183200

Palavras-chave

Cucurbitacin B; EMT; Gefitinib resistant cells; PI3K; ROS

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Chin Med Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido

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