Genetic Engineering Systems to Study Human Viral Pathogens from the Coronaviridae Family.
Mol Biol
; 56(1): 72-89, 2022.
Article
em En
| MEDLINE
| ID: mdl-35194246
ABSTRACT
The COVID-19 pandemic caused by the previously unknown SARS-CoV-2 Betacoronavirus made it extremely important to develop simple and safe cellular systems which allow manipulation of the viral genome and high-throughput screening of its potential inhibitors. In this review, we made an attempt at summarizing the currently existing data on genetic engineering systems used to study not only SARS-CoV-2, but also other viruses from the Coronaviridae family. In addition, the review covers the basic knowledge about the structure and the life cycle of coronaviruses.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Mol Biol
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Federação Russa