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Genetic Engineering Systems to Study Human Viral Pathogens from the Coronaviridae Family.
Galkin, S O; Anisenko, A N; Shadrina, O A; Gottikh, M B.
Afiliação
  • Galkin SO; Bioengineering and Bioinformatics Department, Moscow State University, 119991 Moscow, Russia.
  • Anisenko AN; Chemistry Department, Moscow State University, 119991 Moscow, Russia.
  • Shadrina OA; Bioengineering and Bioinformatics Department, Moscow State University, 119991 Moscow, Russia.
  • Gottikh MB; Chemistry Department, Moscow State University, 119991 Moscow, Russia.
Mol Biol ; 56(1): 72-89, 2022.
Article em En | MEDLINE | ID: mdl-35194246
ABSTRACT
The COVID-19 pandemic caused by the previously unknown SARS-CoV-2 Betacoronavirus made it extremely important to develop simple and safe cellular systems which allow manipulation of the viral genome and high-throughput screening of its potential inhibitors. In this review, we made an attempt at summarizing the currently existing data on genetic engineering systems used to study not only SARS-CoV-2, but also other viruses from the Coronaviridae family. In addition, the review covers the basic knowledge about the structure and the life cycle of coronaviruses.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Mol Biol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Federação Russa
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Mol Biol Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Federação Russa