Associations between visceral fat chronic low back pain and central sensitization in patients with lumbar spinal stenosis.
J Back Musculoskelet Rehabil
; 35(5): 1035-1041, 2022.
Article
em En
| MEDLINE
| ID: mdl-35213342
ABSTRACT
BACKGROUND:
Pain sensitization may be one of the mechanisms contributing to chronic low back pain (CLBP).OBJECTIVE:
To evaluate the association between visceral fat, CLBP, and central sensitization (CS); describe the relationship between low back pain (LBP) intensity and CS; and identify possible correlation between visceral fat and LBP intensity.METHODS:
Patients with CLBP were divided using their CS inventory (CSI) scores into low- (CSI < 40) and high-CSI (CSI ⩾ 40) subgroups. We compared computed tomography (CT) measurements and scores for association with pain according to the visual analogue scale (VAS) between the two groups.RESULTS:
The low-CSI and the high-CSI groups had 47 patients (67.1%; 21 men, 26 women) and 23 patients (32.9%; 11 men and 12 women), respectively. The high-CSI group had a significantly higher mean VAS score (p< 0.01) and estimated mean visceral fat area (p< 0.05) than the low-CSI group. There was a moderate positive correlation between VAS score and visceral fat (standardised partial regression coefficient 0.659, p< 0.01) in the high-CSI group according to multiple linear regression analysis adjusted for age and sex.CONCLUSIONS:
Visceral fat is associated with CLBP, regardless of sex or age, and may be a potential therapeutic target for CLBP with CS.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Estenose Espinal
/
Dor Lombar
/
Dor Crônica
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Male
Idioma:
En
Revista:
J Back Musculoskelet Rehabil
Assunto da revista:
FISIOLOGIA
/
REABILITACAO
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Japão