Low sexual function is associated with menopausal status in mid-aged women with human immunodeficiency virus infection.
Menopause
; 29(3): 317-326, 2022 01 14.
Article
em En
| MEDLINE
| ID: mdl-35213519
ABSTRACT
OBJECTIVE:
To assess the association between menopausal status and female sexual function among mid-aged women with human immunodeficiency virus (HIV) infection.METHODS:
We carried out a cross-sectional study of 221 sexually active HIV-infected women ages 40 to 59âyears, based on a secondary analysis of a three-hospital survey in Lima, Perú. We classified menopausal status according to Stages of Reproductive Aging Workshop criteria (STRAW+10); this exposure variable was categorized as binary (non-postmenopausal and postmenopausal) and-for exploratory analysis-as multinomial (pre-, peri-, and postmenopausal). We defined low sexual function (LSF) using the 6-item Female Sexual Function Index (total score ≤19). Socio-demographic and clinical variables were assessed, including age, used highly active antiretroviral therapy scheme, disease duration, depressive symptoms, and co-morbidities. We performed Poisson generalized linear models with a robust variance to estimate 95% confidence interval (CI), crude prevalence ratios (cPRs), and adjusted prevalence ratios (aPRs) by epidemiological and statistical approaches using nonparametric method of bias-corrected and accelerated bootstrap resampling with 1,000 repetitions.RESULTS:
Studied women had a median age of 47.0âyears (interquartile range 7.5); 25.3% were premenopausal, 25.8% were perimenopausal, and 48.9% were postmenopausal. Also, 64.3% had LSF. The frequency of LSF was 53.6% in non-postmenopausal and 75.0% in postmenopausal women. Postmenopausal status was associated with LSF in both the crude (cPRâ=â1.39; 95% CI 1.13-1.71) and the adjusted regression models (aPRâ=â1.38; 95% CI 1.12-1.71).CONCLUSIONS:
HIV-infected postmenopausal women have a higher prevalence of LSF than those non-postmenopausal ones, even when adjusting for multiple potential confounders.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções por HIV
/
Terapia Antirretroviral de Alta Atividade
Tipo de estudo:
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Middle aged
Idioma:
En
Revista:
Menopause
Assunto da revista:
GINECOLOGIA
Ano de publicação:
2022
Tipo de documento:
Article