Beyond Seizure Control: Treating Comorbidities in Epilepsy via Targeting of the P2X7 Receptor.

Gil, Beatriz; Smith, Jonathon; Tang, Yong; Illes, Peter; Engel, Tobias

Gil, Beatriz; Smith, Jonathon; Tang, Yong; Illes, Peter; Engel, Tobias.

Afiliação

Gil B; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland.
Smith J; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland.
Tang Y; FutureNeuro, Science Foundation Ireland Research Centre for Chronic and Rare Neurological Diseases, Royal College of Surgeons in Ireland, University of Medicine and Health Sciences, D02 YN77 Dublin, Ireland.
Illes P; International Collaborative Centre on Big Science Plan for Purinergic Signaling, Chengdu University of TCM, Chengdu 610075, China.
Engel T; School of Acupuncture and Tuina, Chengdu University of TCM, Chengdu 610075, China.

Int J Mol Sci ; 23(4)2022 Feb 21.

Article em En | MEDLINE | ID: mdl-35216493

Assuntos

Epilepsia/metabolismo; Receptores Purinérgicos P2X7/metabolismo; Convulsões/metabolismo; Animais; Hipocampo/metabolismo; Humanos; Inflamação/metabolismo; Transdução de Sinais/fisiologia

Palavras-chave

ATP; P2X7 receptor; comorbidities; epilepsy; purinergic signalling

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Convulsões / Epilepsia / Receptores Purinérgicos P2X7 Aspecto: Patient_preference Limite: Animals / Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Irlanda País de publicação: Suíça

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