Extracellular Vesicles in Atherosclerosis Research.

Williams, Jessica O; Whelan, Cass; Nash, Jamie; James, Philip E

Williams, Jessica O; Whelan, Cass; Nash, Jamie; James, Philip E.

Afiliação

Williams JO; Cardiff School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, UK.
Whelan C; Cardiff School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, UK.
Nash J; Cardiff School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, UK.
James PE; Cardiff School of Sport and Health Sciences, Cardiff Metropolitan University, Cardiff, UK. PJames@cardiffmet.ac.uk.

Methods Mol Biol ; 2419: 349-359, 2022.

Article em En | MEDLINE | ID: mdl-35237976

RESUMO

The methodologies described in this chapter inform on how to incorporate extracellular vesicles (EV) in model systems to investigate their role in the initiation and progression of the atherosclerotic plaque. The section will cover application of EV in coagulation and thrombus formation, monocytic migration, and adhesion to endothelial monolayers. These methodologies can be used with EV isolated from any cell type and under any conditions.

Assuntos

Aterosclerose; Vesículas Extracelulares; Placa Aterosclerótica; Aterosclerose/metabolismo; Vesículas Extracelulares/metabolismo; Humanos; Monócitos/metabolismo; Placa Aterosclerótica/metabolismo

Palavras-chave

Atherosclerosis; Extracellular vesicles; Monocyte migration; Static adhesion; Thrombus formation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aterosclerose / Placa Aterosclerótica / Vesículas Extracelulares Limite: Humans Idioma: En Revista: Methods Mol Biol Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2022 Tipo de documento: Article País de publicação: Estados Unidos

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