Predicting Mutational Status of Driver and Suppressor Genes Directly from Histopathology With Deep Learning: A Systematic Study Across 23 Solid Tumor Types.

Loeffler, Chiara Maria Lavinia; Gaisa, Nadine T; Muti, Hannah Sophie; van Treeck, Marko; Echle, Amelie; Ghaffari Laleh, Narmin; Trautwein, Christian; Heij, Lara R; Grabsch, Heike I; Ortiz Bruechle, Nadina; Kather, Jakob Nikolas

Loeffler, Chiara Maria Lavinia; Gaisa, Nadine T; Muti, Hannah Sophie; van Treeck, Marko; Echle, Amelie; Ghaffari Laleh, Narmin; Trautwein, Christian; Heij, Lara R; Grabsch, Heike I; Ortiz Bruechle, Nadina; Kather, Jakob Nikolas.

Afiliação

Loeffler CML; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany.
Gaisa NT; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Aachen, Germany.
Muti HS; Institute of Pathology, University Hospital RWTH Aachen, Aachen, Germany.
van Treeck M; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Aachen, Germany.
Echle A; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany.
Ghaffari Laleh N; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Aachen, Germany.
Trautwein C; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany.
Heij LR; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Aachen, Germany.
Grabsch HI; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany.
Ortiz Bruechle N; Center for Integrated Oncology Aachen Bonn Cologne Duesseldorf (CIO ABCD), Aachen, Germany.
Kather JN; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany.

Front Genet ; 12: 806386, 2021.

Article em En | MEDLINE | ID: mdl-35251119

Palavras-chave

TCGA; artificail intelligence (AI); cancer pathway; cancer pathway genes; deep learning; genetic

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Front Genet Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Suíça

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