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Opicapone versus placebo in the treatment of Parkinson's disease patients with end-of-dose motor fluctuation-associated pain: rationale and design of the randomised, double-blind OCEAN (OpiCapone Effect on motor fluctuations and pAiN) trial.
Chaudhuri, K Ray; Odin, Per; Ferreira, Joaquim J; Antonini, Angelo; Rascol, Olivier; Kurtis, Mónica M; Storch, Alexander; Bannister, Kirsty; Soares-da-Silva, Patrício; Costa, Raquel; Magalhães, Diogo; Rocha, José Francisco.
Afiliação
  • Chaudhuri KR; King's College London, Department of Neurosciences, Institute of Psychiatry, Psychology & Neuroscience and Parkinson's Foundation Centre of Excellence, King's College Hospital, London, UK. ray.chaudhuri@kcl.ac.uk.
  • Odin P; Department of Neurology, Lund University, Lund, Sweden.
  • Ferreira JJ; Laboratory of Clinical Pharmacology and Therapeutics, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.
  • Antonini A; Parkinson Disease and Movement Disorder Unit, Department of Neurosciences, University of Padova, Padova, Italy.
  • Rascol O; Toulouse Parkinson Expert Center, Departments of Neurosciences and Clinical Pharmacology, Centre d'Investigation Clinique de Toulouse CIC1436, NS-Park/FCRIN Network, and NeuroToul COEN Center, University Hospital of Toulouse, INSERM, University of Toulouse 3, Toulouse, France.
  • Kurtis MM; Movement Disorders Unit, Neurology Department, Hospital Ruber Internacional, Madrid, Spain.
  • Storch A; Department of Neurology, University Medical Center Rostock, and German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany.
  • Bannister K; Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
  • Soares-da-Silva P; BIAL - Portela & Ca S.A., Coronado, Portugal.
  • Costa R; MedInUP-Center for Drug Discovery and Innovative Medicines, University of Porto, Porto, Portugal.
  • Magalhães D; BIAL - Portela & Ca S.A., Coronado, Portugal.
  • Rocha JF; BIAL - Portela & Ca S.A., Coronado, Portugal.
BMC Neurol ; 22(1): 88, 2022 Mar 12.
Article em En | MEDLINE | ID: mdl-35279112
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson Tipo de estudo: Clinical_trials / Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: BMC Neurol Assunto da revista: NEUROLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson Tipo de estudo: Clinical_trials / Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: BMC Neurol Assunto da revista: NEUROLOGIA Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Reino Unido