A local insulin reservoir in Drosophila alpha cell homologs ensures developmental progression under nutrient shortage.

Ghosh, Suhrid; Leng, Weihua; Wilsch-Bräuninger, Michaela; Barrera-Velázquez, Mariana; Léopold, Pierre; Eaton, Suzanne

Ghosh, Suhrid; Leng, Weihua; Wilsch-Bräuninger, Michaela; Barrera-Velázquez, Mariana; Léopold, Pierre; Eaton, Suzanne.

Afiliação

Ghosh S; Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstraße 108, 01307 Dresden, Germany; Biotechnologisches Zentrum, Technische Universität Dresden, Tatzberg 47/49, 01307 Dresden, Germany. Electronic address: ghosh@mpi-cbg.de.
Leng W; Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstraße 108, 01307 Dresden, Germany.
Wilsch-Bräuninger M; Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstraße 108, 01307 Dresden, Germany.
Barrera-Velázquez M; Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstraße 108, 01307 Dresden, Germany; Undergraduate Program on Genomic Sciences, Centro de Ciencias Genómicas, UNAM, Cuernavaca, Morelos 62210, Mexico.
Léopold P; Institut Curie, PSL Research University, CNRS UMR3215, Inserm U934, 26 Rue d'Ulm, 75005 Paris, France. Electronic address: pierre.leopold@curie.fr.
Eaton S; Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstraße 108, 01307 Dresden, Germany; Biotechnologisches Zentrum, Technische Universität Dresden, Tatzberg 47/49, 01307 Dresden, Germany.

Curr Biol ; 32(8): 1788-1797.e5, 2022 04 25.

Article em En | MEDLINE | ID: mdl-35316653

Assuntos

Proteínas de Drosophila; Somatomedinas; Animais; Drosophila/fisiologia; Proteínas de Drosophila/genética; Proteínas de Drosophila/metabolismo; Drosophila melanogaster/metabolismo; Ecdisona/metabolismo; Insulina/metabolismo; Proteínas de Ligação a Fator de Crescimento Semelhante a Insulina/metabolismo; Larva/metabolismo; Nutrientes; Somatomedinas/metabolismo

Palavras-chave

Drosophila; corpora cardiaca; ecdysone; hormone secretion; insulin; nutrition; prothoracic gland

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Somatomedinas / Proteínas de Drosophila Limite: Animals Idioma: En Revista: Curr Biol Assunto da revista: BIOLOGIA Ano de publicação: 2022 Tipo de documento: Article País de publicação: Reino Unido

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