Liver failure caused by intravenous amiodarone and effective intervention measures: A case report.
J Clin Pharm Ther
; 47(8): 1293-1296, 2022 Aug.
Article
em En
| MEDLINE
| ID: mdl-35322453
ABSTRACT
WHAT IS KNOWN AND OBJECTIVE:
We present a case of intravenous amiodarone-induced liver injury, pharmacy monitoring and its therapy. CASESUMMARY:
A 76-year-old male patient developed acute liver injury 24 h after starting intravenous amiodarone. His liver enzymes improved after discontinuing amiodarone and anti-inflammatory liver therapy, which used reduced glutathione, magnesium isoglycyrrhizinate and ademetionine1,4-butanedisulfonate for injection. WHAT IS NEW ANDCONCLUSION:
Amiodarone is a highly effective antiarrhythmic agent for the treatment and prevention of atrial and ventricular arrhythmias. Acute liver damage after intravenous amiodarone is rare but potentially harmful. Amiodarone loading should be adapted to the necessity of an immediate effect of the drug, and liver function should be monitored closely in critically ill patients. Timely stopped suspected drug and anti-inflammatory liver therapy may reduce the occurrence of drug-induced diseases.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Falência Hepática
/
Amiodarona
Limite:
Aged
/
Humans
/
Male
Idioma:
En
Revista:
J Clin Pharm Ther
Assunto da revista:
FARMACIA
/
TERAPEUTICA
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
China