Preclinical activity of fluvastatin-loaded self-nanoemulsifying delivery system against breast cancer models: Emphasis on apoptosis.

Elimam, Hanan; Hussein, Jihan; Abdel-Latif, Yasmin; Abdel-Aziz, Amal Kamal; El-Say, Khalid M

Elimam, Hanan; Hussein, Jihan; Abdel-Latif, Yasmin; Abdel-Aziz, Amal Kamal; El-Say, Khalid M.

Afiliação

Elimam H; Department of Biochemistry, Faculty of Pharmacy, University of Sadat City, Sadat City, Egypt.
Hussein J; Department of Biochemistry, Faculty of Pharmacy, Sinai University, Kantara, Egypt.
Abdel-Latif Y; Department of Medical Biochemistry, National Research Centre, Giza, Egypt.
Abdel-Aziz AK; Department of Medical Biochemistry, National Research Centre, Giza, Egypt.
El-Say KM; Faculty of Biotechnology, October University for Modern Sciences and Arts (MSA), 6th of October, Giza, Egypt.

J Cell Biochem ; 123(5): 947-963, 2022 05.

Article em En | MEDLINE | ID: mdl-35342983

Assuntos

Carcinoma; Proteína Supressora de Tumor p53; Animais; Apoptose; Caspase 3/metabolismo; Linhagem Celular Tumoral; Fluvastatina/farmacologia; Camundongos; Proteínas Proto-Oncogênicas c-bcl-2/metabolismo

Palavras-chave

apoptosis; fluvastatin; p53; self-nanoemulsifying delivery system; triple-negative breast cancer

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma / Proteína Supressora de Tumor p53 Limite: Animals Idioma: En Revista: J Cell Biochem Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Egito País de publicação: Estados Unidos

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