Autocatalytic oncotherapy nanosystem with glucose depletion for the cascade amplification of hypoxia-activated chemotherapy and H<sub>2</sub>O<sub>2</sub>-dependent chemodynamic therapy.

Hu, Yao; Bai, Song; Fan, Xingyu; Zhou, Fangfang; Chen, Botao; Tan, Songwen; Xu, Hui; Pan, Anqiang; Liang, Shuquan; He, Yongju

Autocatalytic oncotherapy nanosystem with glucose depletion for the cascade amplification of hypoxia-activated chemotherapy and H₂O₂-dependent chemodynamic therapy.

Hu, Yao; Bai, Song; Fan, Xingyu; Zhou, Fangfang; Chen, Botao; Tan, Songwen; Xu, Hui; Pan, Anqiang; Liang, Shuquan; He, Yongju.

Afiliação

Hu Y; School of Materials Science and Engineering, Central South University, Changsha, Hunan 410083, China. heyongju@csu.edu.cn.
Bai S; School of Materials Science and Engineering, Central South University, Changsha, Hunan 410083, China. heyongju@csu.edu.cn.
Fan X; School of Materials Science and Engineering, Central South University, Changsha, Hunan 410083, China. heyongju@csu.edu.cn.
Zhou F; Department of Neurology, the Second Xiangya Hospital of Central South University, Changsha, Hunan 410011, China.
Chen B; Hunan Provincial People's Hospital, the First-Affiliated Hospital of Hunan Normal University, Changsha, Hunan 410005, China.
Tan S; Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, Hunan 410013, China.
Xu H; Institute of Super-Microstructure and Ultrafast Process in Advanced Materials, School of Physics and Electronics, Central South University, Changsha, Hunan 410083, China.
Pan A; School of Materials Science and Engineering, Central South University, Changsha, Hunan 410083, China. heyongju@csu.edu.cn.
Liang S; School of Materials Science and Engineering, Central South University, Changsha, Hunan 410083, China. heyongju@csu.edu.cn.
He Y; School of Materials Science and Engineering, Central South University, Changsha, Hunan 410083, China. heyongju@csu.edu.cn.

Biomater Sci ; 10(9): 2358-2369, 2022 May 04.

Article em En | MEDLINE | ID: mdl-35383789

Assuntos

Nanopartículas; Neoplasias; Pró-Fármacos; Linhagem Celular Tumoral; Glucose; Glucose Oxidase; Humanos; Peróxido de Hidrogênio; Hipóxia; Neoplasias/tratamento farmacológico; Neoplasias/patologia; Pró-Fármacos/farmacologia; Pró-Fármacos/uso terapêutico; Tirapazamina/farmacologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pró-Fármacos / Nanopartículas / Neoplasias Limite: Humans Idioma: En Revista: Biomater Sci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido

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