Manifestation of Herpetic Eye Disease after COVID-19 Vaccine: A UK Case Series.
Ocul Immunol Inflamm
; 30(5): 1136-1141, 2022 Jul.
Article
em En
| MEDLINE
| ID: mdl-35412952
ABSTRACT
PURPOSE:
To highlight the potential risk of herpetic eye disease (HED) reactivation following COVID-19 vaccine.METHODS:
Retrospective analysis of all patients who presented with HED within 28 days post-first dose COVID-19 vaccination.RESULTS:
Eleven eyes (n = 10 patients) were included. The mean interval between COVID-19 vaccination and ocular symptoms/signs was 12.3 ± 10.3 days. Four (40%) patients presented with HSV keratitis, and six (60%) patients presented with VZV keratitis (five had concurrent other signs of herpes zoster ophthalmicus). Common ocular signs included multiple scattered dendritic/pseudodendritic corneal epitheliopathy (90.9%), anterior uveitis (63.6%), and endothelitis (27.3%). All cases were successfully treated with topical and systemic antiviral treatment and/or topical corticosteroids (mean healing time = 3.9 ± 1.6 weeks).CONCLUSIONS:
Our case series highlights the potential temporal association between HED and COVID-19 vaccine. Prophylactic antiviral treatment is recommended in patients with a history of HED prior to COVID-19 vaccination.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Herpes Zoster Oftálmico
/
Ceratite Herpética
/
Vacinas contra COVID-19
/
COVID-19
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Humans
País/Região como assunto:
Europa
Idioma:
En
Revista:
Ocul Immunol Inflamm
Assunto da revista:
ALERGIA E IMUNOLOGIA
/
OFTALMOLOGIA
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Reino Unido