Lanolin Allergic Reactions: North American Contact Dermatitis Group Experience, 2001 to 2018.
Dermatitis
; 33(3): 193-199, 2022.
Article
em En
| MEDLINE
| ID: mdl-35481824
ABSTRACT
BACKGROUND:
Lanolin is an important cause of allergic contact dermatitis.OBJECTIVES:
The aims of this study were to describe the epidemiology of lanolin allergy and to assess trends in patch test reactions to lanolin over time.METHODS:
This study used a retrospective analysis of patients patch tested with lanolin alcohol 30% or Amerchol L-101 50% in petrolatum by the North American Contact Dermatitis Group between 2001 and 2018 (n = 43,691).RESULTS:
Overall, 1431 (3.3%) had a positive reaction, and 1238 (2.8%) were currently relevant. Prevalence of lanolin allergy was 4.63% between 2011 and 2018 (P < 0.0001). Most lanolin-allergic patients had + (52%) reactions; 18%, and 6% had ++ and +++ reactions, respectively. Common primary anatomic sites of dermatitis were the hands (20.7%), scattered/generalized distribution (19.6%), and face (17.0%). Allergic reactions to lanolin were more common in children (4.5%) than in adults (3.2%, P = 0.0018). Compared with nonallergic patients, lanolin-allergic patients were more likely to have history of eczema or hay fever, male sex, older than 40 years, or Black race (P < 0.05). Common lanolin sources were personal care products and drugs/medications. Only 2.24% of the positive reactions were linked to occupation.CONCLUSIONS:
Lanolin sensitivity was common. Reactions were often clinically relevant and linked to personal care products and medications.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Dermatite Alérgica de Contato
/
Cosméticos
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Adult
/
Child
/
Humans
/
Male
País/Região como assunto:
America do norte
Idioma:
En
Revista:
Dermatitis
Assunto da revista:
DERMATOLOGIA
Ano de publicação:
2022
Tipo de documento:
Article