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Short term treatment with a cocktail of rapamycin, acarbose and phenylbutyrate delays aging phenotypes in mice.
Jiang, Zhou; Wang, Juan; Imai, Denise; Snider, Tim; Klug, Jenna; Mangalindan, Ruby; Morton, John; Zhu, Lida; Salmon, Adam B; Wezeman, Jackson; Hu, Jiayi; Menon, Vinal; Marka, Nicholas; Neidernhofer, Laura; Ladiges, Warren.
Afiliação
  • Jiang Z; Department of Comparative Medicine, School of Medicine, University of Washington, Seattle, WA, USA.
  • Wang J; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA.
  • Imai D; Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, CA, USA.
  • Snider T; Department of Veterinary Pathobiology, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK, USA.
  • Klug J; Department of Comparative Medicine, School of Medicine, University of Washington, Seattle, WA, USA.
  • Mangalindan R; Department of Comparative Medicine, School of Medicine, University of Washington, Seattle, WA, USA.
  • Morton J; Department of Comparative Medicine, School of Medicine, University of Washington, Seattle, WA, USA.
  • Zhu L; In Vivo Pharmacology, HD Bioscience Co., Ltd, Shanghai, China.
  • Salmon AB; Department of Molecular Medicine, San Antonio Sam and Ann Barshop Institute for Longevity and Aging Studies, South Texas Veterans Health Care System, Geriatric Research Education and Clinical Center, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
  • Wezeman J; Department of Comparative Medicine, School of Medicine, University of Washington, Seattle, WA, USA.
  • Hu J; Department of Biochemistry, Molecular Biology, and Biophysics, Institute on the Biology of Aging and Metabolism, University of Minnesota, Saint Paul, MN, USA.
  • Menon V; Department of Biochemistry, Molecular Biology, and Biophysics, Institute on the Biology of Aging and Metabolism, University of Minnesota, Saint Paul, MN, USA.
  • Marka N; Clinical and Translational Sciences Institute, Biostatistical Design and Analysis Center, University of Minnesota, Minneapolis, MN, USA.
  • Neidernhofer L; Department of Biochemistry, Molecular Biology, and Biophysics, Institute on the Biology of Aging and Metabolism, University of Minnesota, Saint Paul, MN, USA.
  • Ladiges W; Department of Comparative Medicine, School of Medicine, University of Washington, Seattle, WA, USA. wladiges@uw.edu.
Sci Rep ; 12(1): 7300, 2022 05 04.
Article em En | MEDLINE | ID: mdl-35508491

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sirolimo / Acarbose Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sirolimo / Acarbose Limite: Animals Idioma: En Revista: Sci Rep Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido