Patient and medication-related factors associated with opioid use disorder after inpatient opioid administration.
J Hosp Med
; 17(5): 342-349, 2022 05.
Article
em En
| MEDLINE
| ID: mdl-35570695
ABSTRACT
BACKGROUND:
Examine baseline factors associated with a new diagnosis of opioid use disorder (OUD) within 12 months postdischarge among opioid-naïve patients who received an opioid prescription in the inpatient setting. DESIGN/SETTING:
Retrospective cohort (surgery and nonsurgery) study of opioid-naive patients who had at least one prescription for an opioid during an inpatient hospitalist between 2014 and 2017.PARTICIPANTS:
Twenty-three thousand and thirty-three patients were included.OBJECTIVE:
The primary objective was to determine baseline factors associated with a new OUD diagnosis within 12 months of discharge. Baseline covariates included demographic information, clinical characteristics, medication use, characteristics related to index hospital encounter, and discharge location.FINDINGS:
2.1% of the sample had a new diagnosis of OUD within a year after receiving an opioid during hospital admission. Patients between ages 25 and 34 had higher odds of a new OUD diagnosis compared to those 65 years of age and older (odds ratio [OR] 6.98, 95% confidence interval [CI] 4.02-12.1 [nonsurgery] and 4.69, 95% CI 2.63-8.37 [surgery]). Patients from a high opioid geo-rank region had higher odds of OUD diagnosis (OR 2.08, 95% CI 1.31-3.31 [nonsurgery] and 1.80, 95% CI 1.03-3.15 [surgery]). History of nonopioid-related drug disorder, tobacco use disorder, mental health conditions, and gabapentin use 12 months prior to index date and white race were associated with higher odds of new OUD diagnosis.CONCLUSIONS:
It is important to identify and evaluate factors associated with developing a new diagnosis of OUD following hospitalization. This can inform pain management strategies within the hospital and at discharge, and prompt clinicians to screen for risk of OUD.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Analgésicos Opioides
/
Transtornos Relacionados ao Uso de Opioides
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Humans
Idioma:
En
Revista:
J Hosp Med
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Estados Unidos