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The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies.
Manry, Jérémy; Bastard, Paul; Gervais, Adrian; Le Voyer, Tom; Rosain, Jérémie; Philippot, Quentin; Michailidis, Eleftherios; Hoffmann, Hans-Heinrich; Eto, Shohei; Garcia-Prat, Marina; Bizien, Lucy; Parra-Martínez, Alba; Yang, Rui; Haljasmägi, Liis; Migaud, Mélanie; Särekannu, Karita; Maslovskaja, Julia; de Prost, Nicolas; Tandjaoui-Lambiotte, Yacine; Luyt, Charles-Edouard; Amador-Borrero, Blanca; Gaudet, Alexandre; Poissy, Julien; Morel, Pascal; Richard, Pascale; Cognasse, Fabrice; Troya, Jesús; Trouillet-Assant, Sophie; Belot, Alexandre; Saker, Kahina; Garçon, Pierre; Rivière, Jacques G; Lagier, Jean-Christophe; Gentile, Stéphanie; Rosen, Lindsey B; Shaw, Elana; Morio, Tomohiro; Tanaka, Junko; Dalmau, David; Tharaux, Pierre-Louis; Sene, Damien; Stepanian, Alain; Mégarbane, Bruno; Triantafyllia, Vasiliki; Fekkar, Arnaud; Heath, James R; Franco, José Luis; Anaya, Juan-Manuel; Solé-Violán, Jordi; Imberti, Luisa.
Afiliação
  • Manry J; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, 75015 Paris, France.
  • Bastard P; Imagine Institute, University of Paris, 75015 Paris, France.
  • Gervais A; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, 75015 Paris, France.
  • Le Voyer T; Imagine Institute, University of Paris, 75015 Paris, France.
  • Rosain J; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY 10065.
  • Philippot Q; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, 75015 Paris, France.
  • Michailidis E; Imagine Institute, University of Paris, 75015 Paris, France.
  • Hoffmann HH; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, 75015 Paris, France.
  • Eto S; Imagine Institute, University of Paris, 75015 Paris, France.
  • Garcia-Prat M; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, 75015 Paris, France.
  • Bizien L; Imagine Institute, University of Paris, 75015 Paris, France.
  • Parra-Martínez A; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, 75015 Paris, France.
  • Yang R; Imagine Institute, University of Paris, 75015 Paris, France.
  • Haljasmägi L; Laboratory of Virology and Infectious Disease, Rockefeller University, New York, NY 10065.
  • Migaud M; Laboratory of Virology and Infectious Disease, Rockefeller University, New York, NY 10065.
  • Särekannu K; Department of Pediatrics, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.
  • Maslovskaja J; Pediatric Infectious Diseases and Immunodeficiencies Unit, Hospital Universitari Vall d'Hebron, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, 08035 Barcelona, Spain.
  • de Prost N; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, 75015 Paris, France.
  • Tandjaoui-Lambiotte Y; Imagine Institute, University of Paris, 75015 Paris, France.
  • Luyt CE; Pediatric Infectious Diseases and Immunodeficiencies Unit, Hospital Universitari Vall d'Hebron, Vall d'Hebron Research Institute, Universitat Autònoma de Barcelona, 08035 Barcelona, Spain.
  • Amador-Borrero B; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University, New York, NY 10065.
  • Gaudet A; Institute of Biomedicine and Translational Medicine, University of Tartu, 50090 Tartu, Estonia.
  • Poissy J; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Necker Hospital for Sick Children, 75015 Paris, France.
  • Morel P; Imagine Institute, University of Paris, 75015 Paris, France.
  • Richard P; Institute of Biomedicine and Translational Medicine, University of Tartu, 50090 Tartu, Estonia.
  • Cognasse F; Institute of Biomedicine and Translational Medicine, University of Tartu, 50090 Tartu, Estonia.
  • Troya J; Service de Médecine Intensive Réanimation, Hôpitaux Universitaires Henri Mondor, Assistance Publique-Hôpitaux de Paris, 94010 Créteil, France.
  • Trouillet-Assant S; Groupe de Recherche Clinique Cardiovascular and Respiratory Manifestations of Acute Lung Injury and Sepsis (CARMAS), Faculté de santé de Créteil, Université Paris Est Créteil, 94010 Créteil Cedex, France.
  • Belot A; Hypoxia and Lung, INSERM U1272, Avicenne Hospital, Assistance Publique-Hôpitaux de Paris, 93022 Bobigny, France.
  • Saker K; Sorbonne Université, Hôpital Pitié Salpêtrière, Médecine Intensive Réanimation, Assistance Publique-Hôpitaux de Paris, 75013 Paris, France.
  • Garçon P; INSERM, UMRS 1166-iCAN, Institute of Cardiometabolism and Nutrition, 75013 Paris, France.
  • Rivière JG; Internal Medicine Department, Lariboisière Hospital, Assistance Publique-Hôpitaux de Paris, University of Paris, 75010 Paris, France.
  • Lagier JC; INSERM U1019-CNRS UMR9017, Center for Infection and Immunity of Lille, Institut Pasteur de Lille, University of Lille, 59000 Lille, France.
  • Gentile S; Centre Hospitalier Universitaire, de Lille, Pôle de Réanimation, Hôpital Roger Salengro Lille, 59000 Lille, France.
  • Rosen LB; INSERM U1019-CNRS UMR9017, Center for Infection and Immunity of Lille, Institut Pasteur de Lille, University of Lille, 59000 Lille, France.
  • Shaw E; Centre Hospitalier Universitaire, de Lille, Pôle de Réanimation, Hôpital Roger Salengro Lille, 59000 Lille, France.
  • Morio T; Etablissement Français du Sang, 93218 La Plaine Saint-Denis, France.
  • Tanaka J; Interactions Hôte-Greffon-Tumeur et Ingénierie Cellulaire et Génique (RIGHT), INSERM, Etablissement Français du Sang, Université de Franche-Comté, 25000 Besançon, France.
  • Dalmau D; Etablissement Français du Sang, 93218 La Plaine Saint-Denis, France.
  • Tharaux PL; Santé Ingéniérie Biologie St-Etienne (SAINBIOSE), INSERM U1059, University of Lyon, Université Jean Monnet Saint-Etienne, 42000 Saint-Étienne, France.
  • Sene D; Etablissement Français du Sang, Auvergne-Rhône-Alpes, 42000 Saint-Étienne, France.
  • Stepanian A; Department of Internal Medicine, Infanta Leonor University Hospital, 28031 Madrid, Spain.
  • Mégarbane B; Hospices Civils de Lyon, 69002 Lyon, France.
  • Triantafyllia V; International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, Ecole Nationale Supérieure, Université Claude Bernard Lyon 1 (UCBL), 69365 Lyon, France.
  • Fekkar A; Joint Research Unit, Hospices Civils de Lyon-BioMérieux, Hospices Civils de Lyon, Lyon Sud Hospital, 69495 Pierre-Bénite, France.
  • Heath JR; Hospices Civils de Lyon, 69002 Lyon, France.
  • Franco JL; International Center of Research in Infectiology, Lyon University, INSERM U1111, CNRS UMR 5308, ENS, Ecole Nationale Supérieure, Université Claude Bernard Lyon 1 (UCBL), 69365 Lyon, France.
  • Anaya JM; National Referee Centre for Rheumatic, and Autoimmune and Systemic Diseases in Children, 69000 Lyon, France.
  • Solé-Violán J; Immunopathology Federation Lyon Immunopathology Federation (LIFE), Hospices Civils de Lyon, 69002 Lyon, France.
  • Imberti L; Hospices Civils de Lyon, 69002 Lyon, France.
Proc Natl Acad Sci U S A ; 119(21): e2200413119, 2022 05 24.
Article em En | MEDLINE | ID: mdl-35576468
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autoanticorpos / Interferon Tipo I / Autoimunidade / Anticorpos Neutralizantes / SARS-CoV-2 / COVID-19 Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2022 Tipo de documento: Article País de afiliação: França País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autoanticorpos / Interferon Tipo I / Autoimunidade / Anticorpos Neutralizantes / SARS-CoV-2 / COVID-19 Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2022 Tipo de documento: Article País de afiliação: França País de publicação: Estados Unidos