Retrospective analysis of metabolite patterns of clobazam and N-desmethylclobazam in human plasma by LC-MS/MS.

Bajaj, Amol O; Ly, Diane; Johnson-Davis, Kamisha L

Bajaj, Amol O; Ly, Diane; Johnson-Davis, Kamisha L.

Afiliação

Bajaj AO; ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, Utah, USA.
Ly D; ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, Utah, USA.
Johnson-Davis KL; ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, Utah, USA.

J Mass Spectrom Adv Clin Lab ; 24: 100-106, 2022 Apr.

Article em En | MEDLINE | ID: mdl-35602307

Palavras-chave

CLB, Clobazam; CLIA, Clinical Laboratory Improvement Amendment; CLRW, Clinical Laboratory Reagent Water; Clobazam; DAD, Diode Array Detector; ESI, Electrospray ionization; IRB, Institutional Review Board; LC-MS/MS; LC-MS/MS, liquid chromatography tandem mass spectrometry; LLOQ, lower limit of quantification; LOD, limit of detection; MRM, multiple reaction monitoring; N-CLB, N-desmethylclobazam; N-Desmethylclobazam; Plasma; Retrospective data analysis; TDM, Therapeutic drug monitoring; ULOQ, upper limit of quantification; UV, Ultraviolet

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Mass Spectrom Adv Clin Lab Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Holanda

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