Splenic rupture following lenograstim in post-autologous stem cell transplantation treated with emergency open splenectomy: a case report and literature review.
J Int Med Res
; 50(5): 3000605221095504, 2022 May.
Article
em En
| MEDLINE
| ID: mdl-35638556
ABSTRACT
Granulocyte-colony stimulating factors (G-CSFs) are the cornerstone of peripheral blood stem cell mobilization and apheresis. However, splenic rupture following G-CSF treatment represents a serious and potentially fatal adverse event. Here, we report the case of a patient in their late 50s with severe pancytopenia post-autologous stem cell transplantation reinfusion suffering from splenic rupture after treatment with lenograstim. We also reviewed the literature describing cases of splenic rupture during G-CSF administration.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Ruptura Esplênica
/
Transplante de Células-Tronco Hematopoéticas
Tipo de estudo:
Etiology_studies
Limite:
Humans
Idioma:
En
Revista:
J Int Med Res
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Itália