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RNA polymerase I inhibition induces terminal differentiation, growth arrest, and vulnerability to senolytics in colorectal cancer cells.
Otto, Christoph; Kastner, Carolin; Schmidt, Stefanie; Uttinger, Konstantin; Baluapuri, Apoorva; Denk, Sarah; Rosenfeldt, Mathias T; Rosenwald, Andreas; Roehrig, Florian; Ade, Carsten P; Schuelein-Voelk, Christina; Diefenbacher, Markus E; Germer, Christoph-Thomas; Wolf, Elmar; Eilers, Martin; Wiegering, Armin.
Afiliação
  • Otto C; Experimental Visceral Surgery, Department of General, Visceral, Transplantation, Vascular and Pediatric Surgery (Department of Surgery I), University Hospital Würzburg, Germany.
  • Kastner C; Department of Biochemistry and Molecular Biology, Biocenter, University of Würzburg, Germany.
  • Schmidt S; Department of General, Visceral, Transplantation, Vascular and Pediatric Surgery (Department of Surgery I), University Hospital Würzburg, Germany.
  • Uttinger K; Department of Biochemistry and Molecular Biology, Biocenter, University of Würzburg, Germany.
  • Baluapuri A; Department of General, Visceral, Transplantation, Vascular and Pediatric Surgery (Department of Surgery I), University Hospital Würzburg, Germany.
  • Denk S; Experimental Visceral Surgery, Department of General, Visceral, Transplantation, Vascular and Pediatric Surgery (Department of Surgery I), University Hospital Würzburg, Germany.
  • Rosenfeldt MT; Department of Biochemistry and Molecular Biology, Biocenter, University of Würzburg, Germany.
  • Rosenwald A; Department of Biochemistry and Molecular Biology, Biocenter, University of Würzburg, Germany.
  • Roehrig F; Department of General, Visceral, Transplantation, Vascular and Pediatric Surgery (Department of Surgery I), University Hospital Würzburg, Germany.
  • Ade CP; Institute of Pathology, Universität of Würzburg, Germany.
  • Schuelein-Voelk C; Institute of Pathology, Universität of Würzburg, Germany.
  • Diefenbacher ME; Department of Biochemistry and Molecular Biology, Biocenter, University of Würzburg, Germany.
  • Germer CT; Department of Biochemistry and Molecular Biology, Biocenter, University of Würzburg, Germany.
  • Wolf E; Department of Biochemistry and Molecular Biology, Biocenter, University of Würzburg, Germany.
  • Eilers M; Department of Biochemistry and Molecular Biology, Biocenter, University of Würzburg, Germany.
  • Wiegering A; Department of General, Visceral, Transplantation, Vascular and Pediatric Surgery (Department of Surgery I), University Hospital Würzburg, Germany.
Mol Oncol ; 16(15): 2788-2809, 2022 08.
Article em En | MEDLINE | ID: mdl-35673898
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA Polimerase I / Neoplasias Colorretais Limite: Animals / Humans Idioma: En Revista: Mol Oncol Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA Polimerase I / Neoplasias Colorretais Limite: Animals / Humans Idioma: En Revista: Mol Oncol Assunto da revista: BIOLOGIA MOLECULAR / NEOPLASIAS Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Estados Unidos