Laminar shear stress alleviates monocyte adhesion and atherosclerosis development via miR-29b-3p/CX3CL1 axis regulation.

Pu, Luya; Meng, Qingyu; Li, Shuai; Wang, Yaru; Sun, Banghao; Liu, Bin; Li, Fan

Pu, Luya; Meng, Qingyu; Li, Shuai; Wang, Yaru; Sun, Banghao; Liu, Bin; Li, Fan.

Afiliação

Pu L; Department of Pathogenobiology, The Key Laboratory of Zoonosis, Chinese Ministry of Education, College of Basic Medicine, Jilin University, Changchun, 130021, China.
Meng Q; Department of Pathogenobiology, The Key Laboratory of Zoonosis, Chinese Ministry of Education, College of Basic Medicine, Jilin University, Changchun, 130021, China.
Li S; Department of Pathogenobiology, The Key Laboratory of Zoonosis, Chinese Ministry of Education, College of Basic Medicine, Jilin University, Changchun, 130021, China.
Wang Y; Department of Pathogenobiology, The Key Laboratory of Zoonosis, Chinese Ministry of Education, College of Basic Medicine, Jilin University, Changchun, 130021, China.
Sun B; Department of Immunology, School of Basic Medical Sciences, Xinjiang Medical University, Urumqi, Xinjiang, 830000, China.
Liu B; Cardiovascular Disease Center, The First Hospital of Jilin University, Changchun, 130021, China.
Li F; Department of Pathogenobiology, The Key Laboratory of Zoonosis, Chinese Ministry of Education, College of Basic Medicine, Jilin University, Changchun, 130021, China.

J Cell Sci ; 135(14)2022 07 15.

Article em En | MEDLINE | ID: mdl-35735031

Assuntos

Aterosclerose; MicroRNAs; Animais; Aterosclerose/genética; Aterosclerose/metabolismo; Quimiocina CX3CL1/genética; Quimiocina CX3CL1/metabolismo; Células Endoteliais da Veia Umbilical Humana/metabolismo; Humanos; Camundongos; Camundongos Knockout para ApoE; MicroRNAs/metabolismo; Monócitos/metabolismo; NF-kappa B/genética; NF-kappa B/metabolismo

Palavras-chave

Atherosclerosis; CX3CL1; Laminar shear stress; MiR-29b-3p; Monocyte adhesion

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MicroRNAs / Aterosclerose Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Cell Sci Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido

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