mGWAS-Explorer: Linking SNPs, Genes, Metabolites, and Diseases for Functional Insights.
Metabolites
; 12(6)2022 Jun 07.
Article
em En
| MEDLINE
| ID: mdl-35736459
Tens of thousands of single-nucleotide polymorphisms (SNPs) have been identified to be significantly associated with metabolite abundance in over 65 genome-wide association studies with metabolomics (mGWAS) to date. Obtaining mechanistic or functional insights from these associations for translational applications has become a key research area in the mGWAS community. Here, we introduce mGWAS-Explorer, a user-friendly web-based platform to help connect SNPs, metabolites, genes, and their known disease associations via powerful network visual analytics. The application of the mGWAS-Explorer was demonstrated using a COVID-19 and a type 2 diabetes case studies.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Idioma:
En
Revista:
Metabolites
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Canadá
País de publicação:
Suíça